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Antemortem and Postmortem Measures of Central Nervous System Serotonergic Function: Methodological Issues

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New Directions in Affective Disorders

Abstract

Recent years have seen the emergence of great interest in the function of the serotonergic neurotransmitter system. Research in this area, however, is complicated by the relative inaccessibility of central measures (i.e., cerebrospinal fluid and brain tissue). Compounding this difficulty is the sensitivity of the serotonergic system to a number of variables. We review here a variety of factors that may influence measures of serotonergic activity and briefly discuss the evidence for their impact on these measures.

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© 1989 Springer-Verlag New York Inc.

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Stanley, M., Winchel, R.M. (1989). Antemortem and Postmortem Measures of Central Nervous System Serotonergic Function: Methodological Issues. In: Lerer, B., Gershon, S. (eds) New Directions in Affective Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3524-8_12

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  • DOI: https://doi.org/10.1007/978-1-4612-3524-8_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-96769-1

  • Online ISBN: 978-1-4612-3524-8

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