Role of Endogenous Corticotropin-Releasing Factor in Modulating the Pituitary Response to Stress

  • Catherine Rivier
  • Felice Petraglia
  • Claire-Dominique Walker
  • Wylie Vale
Part of the Hans Selye Symposia on Neuroendocrinology and Stress book series (HANS SELYE SYMP)


The exposure of rats to stressful stimuli results in increased adrenocorticotropic hormone (ACTH) secretion with decreased luteinizing hormone (LH) and growth hormone (GH) release. Since corticotropin-releasing factor (CRF) is also released during stress1, we investigated the possibility that changes in its endogenous levels might mediate the effect of stress on pituitary function.


Luteinizing Hormone Growth Hormone Release Luteinizing Hormone Secretion Luteinizing Hormone Release Plasma Growth Hormone Level 
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Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • Catherine Rivier
  • Felice Petraglia
  • Claire-Dominique Walker
  • Wylie Vale

There are no affiliations available

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