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Neuropeptides and Duodenal Ulcers: The Cysteamine Story

  • Chapter
Neuropeptides and Stress

Part of the book series: Hans Selye Symposia on Neuroendocrinology and Stress ((HANS SELYE SYMP))

Abstract

Biologic stress, defined by Selye1 as “The nonspecific response of the body to any demand”, is a complex neuroendocrine reaction. Although virtually all organs are affected by exposure to stress, the neuroendocrine, cardiovascular and gastrointestinal systems are the first to experience functional changes. Pathologic alterations occur in these organ systems relatively early during the stress reaction, with neuropeptides influencing the development of gastroduodenal ulcers. In the advanced states of ulceration, secondary changes may arise in the systhesis, actions and degradation of hormones, neurotransmitters and neuromodulators.

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Authors
  1. Sandor Szabo
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  2. M. Moriga
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Editor information

Editors and Affiliations

  1. Department of Medicine, Los Angeles School of Medicine, University of California, Los Angeles, California, 90073, USA

    Yvette Taché Ph.D. (Professor and Member) (Professor and Member)

  2. Brain Research Institute, Los Angeles, California, 90024, USA

    Yvette Taché Ph.D. (Professor and Member) & John E. Morley M.D. (Director, Professor and Member) (Professor and Member) &  (Director, Professor and Member)

  3. Geriatric Research, Education, and Clinical Center, Sepulveda Veterans Administration Medical Center, Sepulveda, California, 91343, USA

    John E. Morley M.D. (Director, Professor and Member) (Director, Professor and Member)

  4. Department of Medicine, Los Angeles, School of Medicine, University of California, Los Angeles, California, 90024, USA

    John E. Morley M.D. (Director, Professor and Member) (Director, Professor and Member)

  5. Autonomic Physiology Laboratory, Departments of Medicine and Surgery, San Diego Medical Center, University of California, San Diego, California, 92103, USA

    Marvin R. Brown M.D. (Professor) (Professor)

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Szabo, S., Moriga, M. (1989). Neuropeptides and Duodenal Ulcers: The Cysteamine Story. In: Taché, Y., Morley, J.E., Brown, M.R. (eds) Neuropeptides and Stress. Hans Selye Symposia on Neuroendocrinology and Stress. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3514-9_13

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  • DOI: https://doi.org/10.1007/978-1-4612-3514-9_13

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