Molecular Approaches to Developing a Vaccine for Leprosy
Leprosy, a chronic infectious disease afflicting 10 million to 15 million people, is caused by the obligate intracellular parasite Mycobacterium leprae. Although M. leprae was the first identified bacterial pathogen of man, it remains one of the few human pathogens that cannot yet be grown in culture. The inability to grow leprosy bacillus in culture has severely limited the understanding of the bacillus and the disease.
KeywordsSuppressor Cell Protective Antigen Lepromatous Leprosy Mycobacterium Leprae Obligate Intracellular Parasite
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