Mucosal and Acquired Immunity in Giardiasis and Its Relation to Diarrhea and Malabsorption

  • N. K. Ganguly
  • R. C. Mahajan
Conference paper
Part of the Progress in Vaccinology book series (VACCINOLOGY, volume 2)


Giardiasis is a relatively common intestinal protozoal infection in man and animals (2,46). Several reports indicate that the infection is more common in immunodeficient (3,47) and malnourished (44) hosts and in individuals with a tendency to feco-oral transmission, such as infants in day-care nurseries (8) or homosexuals (52). The disease may occur in both epidemic and endemic forms (40,64). The clinical spectrum of the disease ranges from an entirely asymptomatic infection to a mild, self-limiting illness, or chronic diarrhea with or without malabsorption (34,65). Despite the ubiquitous prevalence of parasites, the pathophysiology of the disease remains obscure. Therefore this chapter reviews the possible mechanism of diarrhea and malabsorption in this increasingly important infection.


Brush Border Membrane Giardia Lamblia Giardia Infection Giardia Trophozoite Bile Salt Deconjugation 
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© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • N. K. Ganguly
  • R. C. Mahajan

There are no affiliations available

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