Gastrointestinal Peptide Binding and Function in the Brain: Emphasis on Peptide YY

  • Akio Inui
  • Shigeaki Baba
Part of the Neuroendocrine Perspectives book series (NEUROENDOCRINE, volume 8)


In the last decade, a large number of gastrointestinal peptides have been found in the brain, some of which fulfill criteria established for neurotransmitters. Several neurons containing a classical transmitter, including catecholamine and acetylcholine, also contain these peptide transmitters (1). Neuropeptides thus act both dependently with and independently from, for example, monoamines (2), either presynaptically through modulation of the release of monoamines, postsynaptically through modulation of the monbaminergic effector response, or through a direct receptor-receptor interaction (3). These factors affect various body functions, including cardiovascular, respiratory, gastrointestinal, endocrine and central nervous system (CNS) functions. Neuropeptide research thus has become one of the most rapidly growing areas of neuroscience.


Corticotropin Release Factor Pancreatic Polypeptide Nucleus Tractus Solitarius Avian Pancreatic Polypeptide Corticotropin Release Factor Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • Akio Inui
  • Shigeaki Baba

There are no affiliations available

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