Gametocytemia and Infectiousness in Falciparum Malaria: Observations and Models

  • Jerry Nedelman
Part of the Advances in Disease Vector Research book series (VECTOR, volume 6)


The interface between the mosquito vector of malaria and the human host is mediated in one direction by the sporozoites, whereby mosquitoes infect humans, and in the other by the gametocytes, whereby humans infect mosquitoes. This paper is about the gametocytes of Plasmodium falciparum and their environment in the human host: when and why gametocytes are produced; patterns of their appearance; the relationship between patent gametocytemia and infectiousness of the host to the vector; and the immune response of the host.


Parasite Density Inoculation Rate Entomological Inoculation Rate Infectious Individual Asexual Parasite 
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Copyright information

© Springer-Verlag New York, Inc. 1989

Authors and Affiliations

  • Jerry Nedelman
    • 1
  1. 1.Department of Mathematical SciencesClemson UniversityClemsonUSA

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