Abstract
Patients with non-insulin-dependent diabetes mellitus (NIDDM) are likely to show selective cognitive decrements relative to age-matched controls—a relationship that has been shown in some but not all studies (cf., Mattlar, Falck, Ronnemaa & Hyyppa, 1985; Perlmuter et al., 1984). While such decrements in cognitive performance might be the result of any of several disease-related alterations in biologic function, a primary etiology may be impaired glucose control (Reaven & Thompson, 1988). The influence of glucose levels and regulation on learning and memory has been demonstrated in humans (Perlmuter, Tun, Sizer, McGlinchey & Nathan, 1987) and animals, diabetic and non-diabetic (Gold & Stone, 1988).
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References
Andres, R. (1971). Aging and diabetes. Medical Clinics in North America, 55, 835–845.
Borkowski, J.G., Benton, A.L., & Spreen, O. (1967). Word fluency and brain damage. Neuropsychologia, 5, 135–140.
Brown, J.S. (1961). The motivation of behavior. New York: McGraw-Hill.
Dakof, G.A., & Mendelsohn, G.A. (1986). Parkinson′ s disease: The psychological aspects of a chronic illness. Psychological Bulletin, 99, 375–387.
Elias, M.F., Robbins, M.A., Schultz, N.R., Jr., & Streeten, D.H.P. (1986). A longitudinal study of neuropsychological test performance for hypertensive and normotensive adults: Initial findings. Journal of Gerontology, 41, 503–505.
Erber, J.T. (1986). Age-related effects of spatial contiguity and interference on coding performance. Journal of Gerontology, 41, 641–644.
Farmer, M.E., White, L.R., Abbott, R.D., Kittner, S.J., Kaplan, E., Wolz, M.M., Brody, J.A., & Wolf, P.A. (1987). Blood pressure and cognitive performance. American Journal of Epidemiology, 126, 1103–1114.
Furchtgott, E., & Busemeyer, J.K. (1979). Heart rate and skin conductance during cognitive processes as a function of age. Journal of Gerontology, 34 183–190.
Geringer, E.S., Perlmuter, L.C., Stern, S.A., & Nathan, D.M. (1988). Depression and diabetic neuropathy: A complex relationship. Journal of Geriatric Psychiatry and Neurology, 1 11–15.
Gold, P.E., & Stone, W.S. (1988). Neuroendocrine effects on memory in aged rodents and humans. Neurobiology of Aging, 9 709–717.
Kausler, D.H., & Kleim, D.M. (1978). Age differences in processing relevant versus irrelevant stimuli in multiple-item recognition learning. Journal of Gerontology, 33, 87–93.
Lichty, W., & Connell, C. (1988). Cognitive functioning of diabetics versus nondiabetics. Presented at the 96th Annual Convention of the American Psychological Association at Atlanta, Georgia.
Light, K.C. (1975). Slowing of response time in young and middle-aged hypertensive patients. Experimental Aging Research, 1, 209–227.
Mattlar, C., Falck, B., Ronnemaa, T., & Hyyppa, M.T. (1985). Neuropsychological cognitive performance of patients with Type-2 diabetes. Scandinavian Journal of Rehabilation Medicine, 17, 101–105.
McFarland, C.E., Jr., Warren, L.R., & Crockard, J. (1985). Memory for self- generated stimuli in young and old adults. Journal of Gerontology, 40, 205–207.
Meuter, F., Thomas, W., Gruneklee, D., Gries, F.A., & Lohmann, R. (1980). Psychometric evaluation of performance in diabetes mellitus. Hormone and Metabolic Research Supplement, 9, 9–17.
Miles, W.R., & Root, H.F. (1922). Psychologic tests applied to diabetic patients. Archives of Internal Medicine, 30, 767–777.
National Diabetes Data Group (1979). Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes: The Journal of the American Diabetes Association, 28, 1039–1057.
Naveh-Benjamin, M. (1988). Recognition memory of spatial location information: Another failure to support automaticity. Memory & Cognition, 16, 437–445.
Perlmuter, L.C., Goldfinger, S.H., Sizer, N.R., & Monty, R.A. (1989). Choosing to improve performance. In P.S. Fry (Ed.), Psychology of Helplessness and Control. Amsterdam: North-Holland Publishers.
Perlmuter, L.C., Hakami, M.K., Hodgson-Harrington, C., Ginsberg, J., Katz, J., Singer, D.E., & Nathan, D.M. (1984). Decreased cognitive function in aging non-insulin-dependent diabetic patients. The American Journal of Medicine, 77, 1043–1048.
Perlmuter, L.C., & Langer, E.J. (1982). The effects of behavioral monitoring on the perception of control. Clinical Gerontologist, 1, 37–43.
Perlmuter, L.C., & Monty, R.A. (1977). The importance of perceived control: Fact or fantasy? American Scientist, 65, 759–765.
Perlmuter, L.C., & Monty, R.A. (1982). Contextual effects on learning and memory. Bulletin of the Psychonomic Society, 20, 290–292.
Perlmuter, L.C., & Monty, R.A. (1986). Vicissitudes of measurement: Depression tests, a case in point. Journal of Social and Clinical Psychology, 4, 475–487.
Perlmuter, L.C., & Nathan, D.M. (1988). Cross sectional and longitudinal analyses of cognitive and biomedical functioning in NIDDM. Unpublished manuscript. Tufts School of Dental Medicine.
Perlmuter, L.C., Nathan, D.M., Goldfinger, S.H., Russo, P.A., Yates, J., & Larkin, M. (1988). Triglyceride levels affect cognitive function in non-insulin dependent diabetics. The Journal of Diabetic Complications, 2 210–213.
Perlmuter, L.C., Tenney, Y.J., & Smith, P.A. (1980). The evaluation and remediation of memory problems in the aged. Technical Report 80-02. Geriatric Research, Educational and Clinical Center, Veterans Administration Outpatient Clinic, Boston, MA.
Perlmuter, L.C., Tun, P., Sizer, N., McGlinchey, R.E., & Nathan, D.M. (1987). Age and diabetes related changes in verbal fluency. Experimental Aging Research, 13, 9–14.
Rand, L.I., Krolewski, A.S., Aiello, L.M., Warram, J.H., Baker, R.S., & Maki, T. (1985). Multiple factors in the prediction of risk of proliferative diabetic retinopathy. The New England Journal of Medicine, 313, 1433–1438.
Reaven, G.M., & Thompson, L.W. (1988). Reduced cognitive function in older patients with non-insulin-dependent diabetes: Relationship to severity of hyperglycemia. Diabetes, 37 (Suppl 1 ), 4A.
Robertson-Tchabo, E.A., Arenberg, D., Tobin, J.D., & Plotz, J.B. (1986). A longitudinal study of cognitive performance in noninsulin dependent (Type II) diabetic men. Experimental Gerontology, 21, 459–467.
Schulman, A.I. (1975). Recognition memory and the recall of spatial location. Memory and Cognition, 3, 256–260.
Solomon, S., Hotchkiss, E., Saravay, S.M., Bayer, C., Ramsey, P., & Blum, R.S. (1983). Impairment of memory function by antihypertensive medication. Archives of General Psychiatry, 40, 1100–1112.
Tun, P.A., Perlmuter, L.C., Russo, P., & Nathan, D.M. (1987). Memory self-assessment and performance in aged diabetics and non-diabetics. Experimental Aging Research, 13, 151–157.
Weisz, J.R. (1983). Can I control it? The pursuit of veridical answers across the life span. In P.B. Bakes & O.G. Brim, Jr. (Eds.), Life span development and behavior, New York: Academic Press.
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Perlmuter, L.C., Goldfinger, S.H., Shore, A.R., Nathan, D.M. (1990). Cognitive Function in Non-Insulin-Dependent Diabetes. In: Holmes, C.S. (eds) Neuropsychological and Behavioral Aspects of Diabetes. Contributions to Psychology and Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3290-2_12
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DOI: https://doi.org/10.1007/978-1-4612-3290-2_12
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