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Cytopathology and Histopathology of the Female Genital Tract in Trichomonas vaginalis Infection

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Trichomonads Parasitic in Humans

Abstract

Four species of trichomonads inhabit humans: Trichomonas vaginalis, described initially by Donné,1 Trichomonads tenax, first seen by O.F. Müller,2 Pentatrichomonas hominis, reported originally by Davaine,3 and Trichomitus fecalis, isolated by Cleveland.4

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References

  1. Donné MA : Animacules observes dans les ma-tières purulentes et le produit des secretions des organes génitaux de Phomme et de la femme. C R Hebd Seances Acad Sci (Paris) 3:385–386, 1836.

    Google Scholar 

  2. Müller OF : Vermium Terrestrium et Fluviatilium seu Animalium Infusorium Helminthicorum et Testaceorum, non Marinorum, Succinta His-toria, vol. 1, pt. 1 and 2. Havnia et Lipsiae: Heineck et Taber, 1773.

    Google Scholar 

  3. Davaine CJ: Traité des Entozoaires et des Mala dies Vermineuses de VHomme et des Animaux Domestiques, 1st ed. Paris: Baillière, 1860.

    Google Scholar 

  4. Cleveland LR : Tritrichomonas fecalis nov. sp. of man: Its ability to grow and multiply indefinitely in faeces diluted with tap water and in frogs and tadpoles. Am J Hyg8:232–255, 1928.

    Google Scholar 

  5. Llewellyn-Jones I: Fundamentals of Obstetrics and Gynecology. London: Färber and Färber, 1970.

    Google Scholar 

  6. Hiemstra I, Van Bel F, Berger HM: Can T. vaginalis cause pneumonia in newborn babies Br Med J 289:355–356, 1984.

    Article  CAS  Google Scholar 

  7. McLaren LC, Davis LE, Healy GR, James CG: Isolation of T. vaginalis from the respiratory tract of infants with respiratory disease. Pediat-rics 71:888–890, 1983.

    CAS  Google Scholar 

  8. Suriyanon V, Nelson KE, Ayudhya VCN: T. vaginalis in a perinephric abscess. Am J Trop Med Hyg 24:776–780, 1975.

    CAS  Google Scholar 

  9. Csonka GW: Trichomoniasis and the dermatologist. Br J Dermatol 90:713–714, 1974.

    Article  PubMed  CAS  Google Scholar 

  10. Kilman J: Trichomoniasis, Diagnose und Therapie. Vienna: Wilhelm Maurdrich, 1973.

    Google Scholar 

  11. Ackers JP, Lumsden WH, Catterall RD, Coyle R: Antitrichomonal antibody in the vaginal secretion of women infected with T. vaginalis. Br J Vener Dis 51:319–323, 1975.

    CAS  Google Scholar 

  12. Chipperfield EJ, Evans BA: The influence of local infection in immunoglobulin formation in the human endocervix. Clin Exp Immunol 11:219–223, 1972.

    PubMed  CAS  Google Scholar 

  13. Green RL, Scales RW, Kraus SJ: Increase of serum immunoglobulin E concentration in veneral disease. Br J Vener Dis 52:247–260, 1976.

    Google Scholar 

  14. Jaakmees HP, Teras JK: Intradermal reaction with specific antigen in cases of genito-urinary trichomoniasis. Wiad Parazytol 12:385–391, 1966.

    Google Scholar 

  15. Frost JK, Honigberg BM: Comparative pathogenicity of Trichomonas vaginalis and Trichomonas gallinae for mice. II. Histopathology of subcutaneous lesions. J Parasitol 48:898–918, 1962.

    CAS  Google Scholar 

  16. Honigberg BM, Livingston MC, Frost JK: Pathogenicity of fresh isolates of T. vaginalis: “the mouse assay” versus clinical and pathologic findings. Acta Cytol 10:353–361, 1966.

    PubMed  CAS  Google Scholar 

  17. Honigberg BM, Gupta PK, Spence MR, Frost JK, Kuczyiiska K, Choromanski L, Warton A: Pathogenicity of Trichomonas vaginalis: Cyto-pathologic and histopathologic changes of the cervical epithelium. Obstet Gynecol 64:179–184, 1984.

    PubMed  CAS  Google Scholar 

  18. Kulda J, Honigberg BM, Frost JK, Hollander DH: Pathogenicity of Trichomonas vaginalis. Am J Obstet Gynecol 108:908–918, 1970.

    PubMed  CAS  Google Scholar 

  19. Frost JK: Gynecologic and obstetric cytopathol-ogy. In Novak ER, Woodruff JD (eds): Novak’s Gynecologic and Obstetric Pathology With Clinical and Endocrine Relations, 8th ed, pp 634–728. Philadelphia: WB Saunders, 1979.

    Google Scholar 

  20. Jirovec O, Petrü M: T. vaginalis and trichomoniasis. Adv Parasitol 6:117–186, 1968.

    Article  PubMed  CAS  Google Scholar 

  21. Trussell RE : Trichomonas vaginalis and Trichomoniasis, pp 113–124. Springfield, I11: Charles C Thomas, 1947.

    Google Scholar 

  22. Honigberg BM: Trichomonads of importance in human medicine. In Kreier JP (ed): Parasitic Protozoa, vol 2, pp 276–454. New York: Academic Press, 1978.

    Google Scholar 

  23. Wisdom AR, Dunlop EMC: Trichomoniasis: Study of the disease and its treatment in women and men. Br J Vener Dis 41:90–96, 1965.

    PubMed  CAS  Google Scholar 

  24. Brown MT: Trichomoniasis. Practitioner 209: 639–644, 1972.

    PubMed  CAS  Google Scholar 

  25. Mason PR: Trichomoniasis. New ideas on an old disease. S Afr Med J 58:857–858, 1980.

    CAS  Google Scholar 

  26. Wallin JE, Thompson SE, Saidi A, Wong KH: Urethritis in women attending an STD clinic. Br J Vener Dis 57:50–54, 1981.

    PubMed  CAS  Google Scholar 

  27. Peterson WF, Stauch JE, Ryder CD: Metronidazole in pregnancy. Am J Obstet Gynecol 94:343–349, 1966.

    Google Scholar 

  28. Gallai Z, Sylvestre L: The present status of urogenital trichomoniasis: A general review of literature. Appl Ther 8:773–778, 1966.

    PubMed  CAS  Google Scholar 

  29. Mardh PA, Westrom L: Tubal and cervical cultures in acute salpingitis with special reference to Mycoplasma hominis and T -strain mycoplasmas. Br J Vener Dis 46:179–186, 1970.

    PubMed  CAS  Google Scholar 

  30. Keith LG, Berger GS, Edelman DA, Newton W, Fullan N, Bailey R, Friberg J: On the causation of pelvic inflammatory disease. Am J Obstet Gynecol 149:215–223, 1984.

    PubMed  CAS  Google Scholar 

  31. Catterall RD: Trichomonal infections of the genital tract. Med Clin North Am 56:1203–1209, 1972.

    PubMed  CAS  Google Scholar 

  32. Rein MF, Müller M: Trichomonas vaginalis. In Holmes KK, Mardh PA, Weisner PH: Sexually Transmitted Diseases, pp 525–536. New York: McGraw-Hill, 1984.

    Google Scholar 

  33. Fouts AC, Kraus SJ: Trichomonas vaginalis: Re-evaluation of its clinical presentation and laboratory diagnosis. J Infect Dis 141:137–143, 1980.

    Article  PubMed  CAS  Google Scholar 

  34. Berggren O: Association of carcinoma of the uterine cervix and Trichomonas vaginalis infestations: Frequency of Trichomonas vaginalis in preinvasive and invasive cervical carcinoma. Am J Obstet Gynecol 105:166–168, 1969.

    PubMed  CAS  Google Scholar 

  35. Frost JK: Trichomonas vaginalis and cervical epithelial changes. Ann NY Acad Sci 97:792–799, 1962.

    Article  PubMed  CAS  Google Scholar 

  36. Grice AC: Vaginal infection causing spontaneous rupture of the membranes and premature delivery. Aust NZ J Obstet Gynaecol 14:156–158, 1974.

    Article  Google Scholar 

  37. Mason PR, Brown IM: Trichomoniasis in pregnancy. Lancet 2:1024–1026, 1980.

    Google Scholar 

  38. Robinson SC, Halifax NS: Observations on vaginal trichomoniasis. I. In pregnancy. Can Med Assoc J 84:948–949, 1961.

    CAS  Google Scholar 

  39. Gupta PK, Frost JK: Human urogenital trichomoniasis: Epidemiology, clinical and pathological manifestations. In Kulda J, Cerkasov J (eds): Proc Int Symp Trichomonads & Trichomoniasis, Prague, July, 1985 (Post-Symp Publ, Pt 2). Acta Univ Carolinae (Prague) Biol 30:339–410 (1986) 1988.

    Google Scholar 

  40. Hypes RA, Ladewig PP: Leukocytic clusters on epithelial cells in cervicovaginal smears: A presumptive test for Trichomonas infection. Am J Clin Pathol 26:94–97, 1956.

    PubMed  CAS  Google Scholar 

  41. Naib ZM : Exfoliative Cytopathology, 3rd ed, pp 95–99. Boston: Little, Brown & Co, 1985.

    Google Scholar 

  42. Sun T : Trichomoniasis. In Sun T (ed): Sexually Related Infectious Diseases: Clinical and Laboratory Aspects, pp 179–185. New York: Field, Rich and Associates, 1986.

    Google Scholar 

  43. Bibbo M , Harris MJ, Wied GL: Microbiology of the female genital tract. In Compendium on Diagnostic Cytology, 5th ed, pp 50–51. Chicago: Tutorials of Cytology, University of Chicago Press, 1983.

    Google Scholar 

  44. Winston RML: The relation between size and pathogenicity of Trichomonas vaginalis. J Obstet Gynaecol Br Commonw 81:399–404, 1974.

    Article  PubMed  CAS  Google Scholar 

  45. Mehta SH, Verma K: Relationship between size and pathogenicity of Trichomonas vaginalis. Indian J Med Res 74:231–235, 1981.

    PubMed  CAS  Google Scholar 

  46. Koss LG, Wolinska WH: Trichomonas vaginalis cervicitis and its relationship to cervical cancer. Cancer 12:1171–1193, 1959.

    Article  PubMed  CAS  Google Scholar 

  47. Nielsen MH, Nielsen R: Electron microscopy of Trichomonas vaginalis Donné: Interaction with vaginal epithelium in human trichomoniasis. Acta Pathol Microbiol Immunol Scand (B) 83:305–320, 1975.

    CAS  Google Scholar 

  48. Frost JK, Honigberg BM, McLure MT: Intracellular Trichomonas vaginalis and Trichomonas gallinae in natural and experimental infections. J Parasitol 47:302–303, 1961.

    Article  Google Scholar 

  49. Gardner WA, Culberson DE, Bennett BD: Trichomonas vaginalis in the prostate gland. Arch Pathol Lab Med 110:430–432, 1986.

    PubMed  Google Scholar 

  50. Frost JK : Morphologic characteristics of re-troplasia: Decreased general activity. In Frost JK: The Cell in Health and Disease, 2nd edn., Chapter 7, pp. 97–109. In Wied GL (ed): Monographs in Clinical Cytology, vol 2, Basel, New York: S. Karger, 1986.

    Google Scholar 

  51. Kolstad P: The colposcopic picture of Trichomonas vaginitis. Acta Obstet Gynecol Scand 43:388–398, 1964.

    Article  PubMed  CAS  Google Scholar 

  52. Tamayo JG, Nunez Monteil JT, de Garcia HP: An electron microscopic investigation on the pathogenesis of human vaginal trichomoniasis. Acta Cytol 22:447–455, 1978.

    Google Scholar 

  53. Gardner HL, Fernet P: Etiology of vaginitis emphysematosa. Am J Obstet Gynecol 88:680–794, 1964.

    PubMed  CAS  Google Scholar 

  54. Wilbanks GD, Carter B: Vaginitis emphysematosa. Obstet Gynecol 22:301–309, 1963.

    PubMed  CAS  Google Scholar 

  55. Newton WL, Reardon LV, DeLeva AM: A comparative study of the subcutaneous inoculation of germ-free and conventional guinea pigs with two strains of Trichomonas vaginalis. Am J Trop Med Hyg 9:56–61, 1960.

    PubMed  CAS  Google Scholar 

  56. Honigberg BM : Comparative pathogenicity of Trichomonas vaginalis and Trichomonas galli-nae to mice. I. Gross pathology, quantitative evaluation of virulence, and some factors affecting pathogenicity. J Parasitol 47:545–571, 1961.

    Article  PubMed  CAS  Google Scholar 

  57. Honigberg BM, King VM: Structure of Trichomonas vaginalis Donné. J Parasitol 50:345–364, 1964.

    Article  PubMed  CAS  Google Scholar 

  58. Allen E, Baum H: The treatment of vaginitis. Am J Obstet Gynecol 45:246–254, 1943.

    Google Scholar 

  59. Naib ZM : Stepping up the search for vaginal pathogens. In Richart RM (mod): Symposium. Contemp Obstet/Gynecol, Oct/Dec: 139–149, 194–215, 1984.

    Google Scholar 

  60. Rodgerson EB : Vulvovaginal papillomas and Trichomonas vaginalis. Obstet Gynecol 40:327–333, 1972.

    PubMed  CAS  Google Scholar 

  61. Meisels A: Dysplasia and carcinoma of the uterine cervix. IV. A correlated cytologic and histologic study with special emphasis on vaginal microbiology. Acta Cytol 13:224–231, 1969.

    CAS  Google Scholar 

  62. Kaarma H, Ter as JK, Podar U: Histological changes in the vaginal part of the uterus in cases of genitourinary trichomonadosis. Wiad Parazytol 15:319–321, 1969.

    CAS  Google Scholar 

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Gupta, P.K., Frost, J.K. (1990). Cytopathology and Histopathology of the Female Genital Tract in Trichomonas vaginalis Infection. In: Honigberg, B.M. (eds) Trichomonads Parasitic in Humans. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3224-7_14

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  • DOI: https://doi.org/10.1007/978-1-4612-3224-7_14

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7922-8

  • Online ISBN: 978-1-4612-3224-7

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