Olfaction and Neuropsychiatry

  • Michael J. Serby
  • Pamela M. Larson
  • Davina Kalkstein


Olfactory performance is impaired in a variety of neurological and psychiatric disorders. This chapter will review work accomplished in some of these disorders, most notably Alzheimer’s disease (AD), depression, schizophrenia, and the dementia of the acquired immune deficiency syndrome (AIDS). There is a major focus on AD, reflecting the thrust of our own research and the recent emphasis on olfactory changes in this dementia. Olfactory testing has proved to be a safe and productive method of gaining information about the central nervous system (CNS). We have used tests of odor detection and identification to investigate a number of clinical and basic science questions pertinent to AD. The findings in major depression, schizophrenia, and AIDS are more restricted and preliminary in nature. It is hoped that these studies will engender further understanding of CNS diseases.


Olfactory Function Olfactory Dysfunction Odor Identification Odor Detection Global Deterioration Scale 
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© Springer-Verlag New York Inc. 1992

Authors and Affiliations

  • Michael J. Serby
  • Pamela M. Larson
  • Davina Kalkstein

There are no affiliations available

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