Chemical Aspects of Neuronal Information Transmission in Synapses

  • Hinrich Rahmann
  • Mathilde Rahmann


The totality of mechanisms involved in the process of information transmission is immensely complex, comprised as it is of biochemical, biophysical, and ultrastructural elements. More-over, these are not identical for all types of nerve terminals. Indeed, quite heterogeneous varieties have become apparent.


Nerve Terminal Synaptic Cleft Postsynaptic Membrane Neurosecretory Cell Luteinizing Hormone Release Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Abrams TW, Kandel ER (1985) Roles of calcium and adenylate cyclase in activity-dependent facilitation, a cellular mechanism for classical conditioning in Aplysia. Neurosci Abstr.Google Scholar
  2. McGeer PL, Eccles JC, McGeer EG (1987) Molecular neurobiology of the mammalian brain. Plenum Press, New York LondonGoogle Scholar
  3. Gibson GE, Peterson C (1985) Calcium and the aging nervous system. Neurobiol Aging 8: 329–343CrossRefGoogle Scholar
  4. Hayashi K, Mühleisen M, Probst W, Rahmann H (1984) Binding of (Ca2+) to phosphoinositols, phosphatidyl-serines and gangliosides. Chem Phys Lipids 34:317–322PubMedCrossRefGoogle Scholar
  5. Hucho F (1986) Neurochemistry, fundamentals and concepts. VCH, WeinheimGoogle Scholar
  6. Iversen LL (1984) Die Chemie der Signalübertragung im Gehirn. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 21–31Google Scholar
  7. Kandel ER (1981) Calcium and the control of synaptic strength by learning. Nature 293: 697–700PubMedCrossRefGoogle Scholar
  8. Kandel ER (1984) Kleine Verbände von Nervenzellen. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 77–85Google Scholar
  9. Kandel ER, Schwartz JH (eds) (1985) Principles of neural science, 2nd edn. Elsevier Science, AmsterdamGoogle Scholar
  10. Katz JJ, Halstead WC (1950) Protein organisation and mental function. Comp Psychol Monogr 20:1–38Google Scholar
  11. Keynes RD (1984) Ionenkanäle in Nervenmembranen. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 15–19Google Scholar
  12. Krnjevic K (1974) Chemical nature of synaptic transmission in vertebrates. Physiol Rev 54: 418–505Google Scholar
  13. Mühleisen M, Probst W, Hayashi K, Rahmann H (1983) Calcium binding to liposomes composed of negatively charged lipid moieties. Jpn J Exp Med 53:103–107PubMedGoogle Scholar
  14. Nishizuka Y (1984) Turnover of phospholipids and signal transduction. Science 225: 1365–1370PubMedCrossRefGoogle Scholar
  15. Patterson PH, Potter DD, Furshpan EJ (1984) Chemische Differenzierung von Nervenzellen. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 45–62Google Scholar
  16. Pfenninger KH (1973) Synaptic morphology and cytochemistry. Fischer, StuttgartGoogle Scholar
  17. Popper KR, Eccles JC (1982) Das Ich und sein Gehirn. Piper, München ZürichGoogle Scholar
  18. Rahmann H (1976) Neurobiologie. Ulmer, Stuttgart (UTB)Google Scholar
  19. Rahmann H (1983) Functional implication of gangliosides in synaptic transmission (Critique). Neurochemistry International 5: 539–547PubMedCrossRefGoogle Scholar
  20. Rahmann H (1983) Lernen und Gedächtnis sowie Aspekte der Gedächtnissteigerung vom Standpunkt der Neurobiologie. In: Fischer B, Lehrl S (Hrsg) Gehirn-Jogging (biologische und informationspsychologische Grundlagen des zerebralen Jogging). Narr, Tübingen, S 28–44Google Scholar
  21. Rahmann H (1985) Hirnganglioside der Wirbeltiere und ihre funktionelle Bedeutung bei der synaptischen Informationsübertragung. In: Evolution, Festschrift f. Bernhard Rensch. Aschendorf f, Münster (Schriftenreihe d. Westf. Wilhelmsuniversität Münster, Bd 4, S 8–50)Google Scholar
  22. Rahmann H (1985) Gedächtnisbildung durch molekulare Bahnung in Synapsen mit Gangliosiden. Funkt Biol Med 4:249–261Google Scholar
  23. Rahmann H, Probst W (1986) Ultrastructural localization of calcium at synapses and modulatory interactions with gangliosides. In: Tettamanti G, Ledeen RW, Sandhoff K, Nagai Y, Toffano G (eds) Gangliosides and neuronal plasticity. Liviana Press, Padova (Fidia Research Series, pp 125—135)Google Scholar
  24. Routtenberg A (1984) Das Belohnungssystem des Gehirns. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 160–167Google Scholar
  25. Schade J (1973) Die Funktion des Nervensystems. Fischer, StuttgartGoogle Scholar
  26. Schmidt RF (Hrsg) (1987) Grundriß der Neurophysiologie, 6. Aufl. Springer, Berlin Heidelberg New York London Paris Tokyo (HTB)Google Scholar
  27. Schmidt RF, Thews G (Hrsg) (1980) Physiologie des Menschen, 20. Aufl. Springer, Berlin Heidelberg New YorkGoogle Scholar
  28. Shapiro E, Castellucci VF, Kandel ER (1980) Presynaptic inhibition in Aplysia involves a decrease in the Ca2+-current of the presynaptic neuron. Proc Natl Acad Sci USA 77: 1185–1189PubMedCrossRefGoogle Scholar
  29. Shepherd GM (1983) Neurobiology. Oxford University Press, New York OxfordGoogle Scholar
  30. Singer W (1985) Hirnentwicklung und Umwelt. Spektrum der Wissenschaft: 48–61Google Scholar
  31. Sinz R (1978) Gehirn und Gedächtnis. Fischer, Stuttgart New York (UTB 852)Google Scholar
  32. Smith SJ, Augustine GJ, Charlton MP (1985) Transmission at voltage-clamped giant synapse of the squid: Evidence for cooperativity of presynaptic calcium action. Proc Natl Acad Sci USA 82:622–625PubMedCrossRefGoogle Scholar
  33. Snyder SH (1985) Signalübertragung zwischen Zellen. Spektrum der Wissenschaft: 126–135Google Scholar
  34. Stevens CF (1984) Die Nervenzelle. In: Gehirn und Nervensystem. Spektrum der Wissenschaft: 3–14Google Scholar
  35. Weinberg CB, Sanes JR, Hall ZW (1981) Formation of neuromuscular junction in adult rats: accumulation of acetylcholine receptors, acetylcholinesterase, and compounds of synaptic basal lamina. Dev Biol 84:255–266PubMedCrossRefGoogle Scholar
  36. Whittaker VP, Gray EG (1962) The synapse: Biology and morphology. Br Med Bull 18: 223–228PubMedGoogle Scholar
  37. Whittaker VP, Michaelson IA, Kirkland RJA (1964) The separation of synaptic vesicles from nerve ending particles (synaptosomes). Biochem J 90:293–303PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1992

Authors and Affiliations

  • Hinrich Rahmann
    • 1
  • Mathilde Rahmann
    • 1
  1. 1.Zoologisches InstitutUniversität Stuttgart-HohenheimStuttgartGermany

Personalised recommendations