Interstitial cystitis usually occurs in elderly women, who present with lower abdominal or perineal pain and urinary frequency. The lesion can involve anywhere in the bladder. Histologically, the lesion is a mucosal ulceration covered by fibrin and necrotic material. The underlying lamina propria and muscularis show edema, hemorrhage, granulation tissue, and a mononuclear cell infiltrate. Mast cells are frequently observed (Fig. 14.1).


Bladder Cancer Transitional Cell Carcinoma Interstitial Cystitis Pleomorphic Carcinoma Inverted Papilloma 
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Copyright information

© Springer-Verlag New York, Inc. 1992

Authors and Affiliations

  • Kitai Kim
    • 1
    • 2
  • Bernard Naylor
    • 3
    • 4
  1. 1.Medical College of OhioToledoUSA
  2. 2.Medical College HospitalsToledoUSA
  3. 3.The University of MichiganAnn ArborUSA
  4. 4.The University of Michigan HospitalsAnn ArborUSA

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