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Cell Interactions in Trophoblast Invasion

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Trophoblast Cells

Part of the book series: Serono Symposia, USA Norwell, Massachusetts ((SERONOSYMP))

Abstract

The extent of trophoblastic penetration of the uterine wall during placentation varies widely between species, but nowhere is it more extensive than in the human (1, 2). Certain pathological conditions of pregnancy show either insufficient (preeclampsia and intrauterine growth retardation) or excessive (placenta percreta) trophoblastic penetration of adjacent maternal tissues and have been suggested to be caused by maternal rather than fetal abnormalities (3, 4). In order to diagnose and treat these pathologies, a greater understanding of the normal control of trophoblast invasion is a necessity. This chapter therefore concentrates on interactions between trophoblast and endometrium in the human, but reference is made to other species where comparison is thought to be instructive. This is most often the case in certain primates and rodents that show interstitial implantation.

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Authors
  1. John D. Aplin
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  2. Ljiljana Vićovac
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  3. Abdul Sattar
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Kansas Medical Center, 66160, Kansas City, KS, USA

    Michael J. Soares Ph.D.

  2. Department of Biology, Sinsheimer Laboratories, University of California, 95064, Santa Cruz, CA, USA

    Frank Talamantes Ph.D.

  3. Division of Endocrinology, Children’s Hospital Medical Center, 45229, Cincinnati, OH, USA

    Stuart Handwerger M.D.

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© 1993 Springer-Verlag New York, Inc.

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Aplin, J.D., Vićovac, L., Sattar, A. (1993). Cell Interactions in Trophoblast Invasion. In: Soares, M.J., Talamantes, F., Handwerger, S. (eds) Trophoblast Cells. Serono Symposia, USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2718-2_6

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  • DOI: https://doi.org/10.1007/978-1-4612-2718-2_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7641-8

  • Online ISBN: 978-1-4612-2718-2

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