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Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family

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Trophoblast Cells

Part of the book series: Serono Symposia, USA Norwell, Massachusetts ((SERONOSYMP))

Abstract

Normal growth and maturation of a specialized extraembryonic structure, the placenta, are essential for the establishment and maintenance of pregnancy. The placenta acts as the interface between maternal and embryonic compartments, developing in parallel with the embryo and facilitating the acquisition of maternal resources required for embryonic and fetal development. This essential responsibility of the placenta is accomplished in a number of important ways, including (i) regulation of the transport of nutrients and wastes, (ii) an immunologic role in preventing fetal rejection, and (iii) an endocrine/communication/signaling role between fetal and maternal compartments. Consequently, understanding the control of placental development is fundamental to an appreciation of the initiation and maintenance of pregnancy and various abnormalities associated with altered growth and development. The cells responsible for these diverse functions of the placenta are trophoblast cells.

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Authors
  1. Michael J. Soares
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  2. Teresa N. Faria
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  3. Gary P. Hamlin
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  4. Xing-Jian Lu
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  5. Santanu Deb
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Kansas Medical Center, 66160, Kansas City, KS, USA

    Michael J. Soares Ph.D.

  2. Department of Biology, Sinsheimer Laboratories, University of California, 95064, Santa Cruz, CA, USA

    Frank Talamantes Ph.D.

  3. Division of Endocrinology, Children’s Hospital Medical Center, 45229, Cincinnati, OH, USA

    Stuart Handwerger M.D.

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© 1993 Springer-Verlag New York, Inc.

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Soares, M.J., Faria, T.N., Hamlin, G.P., Lu, XJ., Deb, S. (1993). Trophoblast Cell Differentiation: Expression of the Placental Prolactin Family. In: Soares, M.J., Talamantes, F., Handwerger, S. (eds) Trophoblast Cells. Serono Symposia, USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2718-2_4

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  • DOI: https://doi.org/10.1007/978-1-4612-2718-2_4

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7641-8

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