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Dosage Analysis Using B-A Translocations

  • James A. Birchler
Part of the Springer Lab Manuals book series (SLM)

Abstract

Dosage studies are useful for localizing the structural genes for certain gene products, most notably enzymes; for the study of dosage-sensitive regulatory effects (Birchler and Newton 1981); for determination of mutants as null or leaky or gain of function (Poethig, 1988); or for introduction of more than one copy from a single parent as a test of parental imprinting (Kermicle 1970). The tools available in maize for dosage studies are the most extensive in any diploid plant species and for overall utility, rival those in any higher eukaryote. The basis for the dosage series depends on the nondisjunction property of the B chromosome centromere described in previous chapters on B-A translocations.

Keywords

Dosage Study Normal Chromosome Female Side Color Marker Allozyme Marker 
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References

  1. Birchler JA (1979) A study of enzyme activities in a dosage series of the long arm of chromosome one in maize. Genetics 92: 1211–1229PubMedGoogle Scholar
  2. Birchler JA (1980) The genetic basis of dosage compensation of alcohol dehydrogenase-1 in maize. Genetics 97: 625–637Google Scholar
  3. Birchler JA, Newton KJ (1981) Modulation of protein levels in chromosomal dosage series of maize: the biochemical basis of aneuploid syndromes. Genetics 99: 247–266PubMedGoogle Scholar
  4. Kermicle JL (1970) Dependence of the R-mottled aleurone phenotype in maize on mode of sexual transmission. Genetics 66: 69–85PubMedGoogle Scholar
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  6. Wendel JF (1989) Chromosomal locations of isozyme loci in maize (Zea mays L.) Isozyme Bulletin 22: 33–35Google Scholar

Copyright information

© Springer-Verlag New York, Inc. 1994

Authors and Affiliations

  • James A. Birchler

There are no affiliations available

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