Dosage Analysis Using B-A Translocations

  • James A. Birchler
Part of the Springer Lab Manuals book series (SLM)


Dosage studies are useful for localizing the structural genes for certain gene products, most notably enzymes; for the study of dosage-sensitive regulatory effects (Birchler and Newton 1981); for determination of mutants as null or leaky or gain of function (Poethig, 1988); or for introduction of more than one copy from a single parent as a test of parental imprinting (Kermicle 1970). The tools available in maize for dosage studies are the most extensive in any diploid plant species and for overall utility, rival those in any higher eukaryote. The basis for the dosage series depends on the nondisjunction property of the B chromosome centromere described in previous chapters on B-A translocations.


Dosage Study Normal Chromosome Female Side Color Marker Allozyme Marker 
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© Springer-Verlag New York, Inc. 1994

Authors and Affiliations

  • James A. Birchler

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