Patent Ductus Arteriosus

  • Bradley J. Harlan
  • Albert Starr
  • Fredic M. Harwin
  • Alain Carpentier


Robert Gross stated that his first ligation of a patent ductus arteriosus in 1938 “formed the opening wedge in the surgical attack on congenital cardiovascular anomalies.”9 Ligation or division of the ductus has become a simple procedure associated with almost no morbidity or mortality. However, the complication of operative hemorrhage from a torn or insufficiently sutured ductus is so serious that the operation should always be approached with respect, proper planning, and meticulous technique.


Premature Infant Aortic Arch Recurrent Laryngeal Nerve Patent Ductus Arteriosus Transcatheter Closure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Abbott ME: Atlas of Congenital Cardiac Disease. New York, American Heart Association, 1936, p 61.Google Scholar
  2. 2.
    Allen HD, Sahn DJ, Goldberg SJ: New serial contrast technique for assessment of the left to right shunting patent ductus arteriosus in the neonate. Am J Cardiol 41: 288,1978.PubMedCrossRefGoogle Scholar
  3. 3.
    Black LL, Goldman BS: Surgical treatment of the patent ductus arteriosus in the adult. Ann Surg 175:290,1972.PubMedCrossRefGoogle Scholar
  4. 4.
    Campbell N: Natural history of persistent ductus arteriosus. Br Heart J 30:4,1968.PubMedCrossRefGoogle Scholar
  5. 5.
    Clark DR, Paton BC, Way GL, Stewart JR: Patent ductus arteriosus ligation and respiratory distress syndrome in premature infants. Ann Thorac Surg 22:138,1976.CrossRefGoogle Scholar
  6. 6.
    Cooley DA: Techniques in Cardiac Surgery, 2nd ed. Philadelphia, WB Saunders Co, 1984, p 31.Google Scholar
  7. 7.
    Friedman WF, Hirschklau MJ, Printz MP, Pitlick PT, Kirkpatrick SE: Pharmacologic closure of patent ductus arteriosus in the premature infant. N Engl J Med 295:526,1976.PubMedCrossRefGoogle Scholar
  8. 8.
    Gersony WM, Peckham GJ, Ellison RC, Miettinen OS, Nadas AS: Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study. J Pediatr 102:895,1983.PubMedCrossRefGoogle Scholar
  9. 9.
    Gross RE: The patent ductus arteriosus: observation on diagnosis and therapy in 525 surgically treated cases. Am J Med 12:472,1952.PubMedCrossRefGoogle Scholar
  10. 10.
    Gross RE, Hubbard JP: Surgical ligation of a patent ductus arteriosus. Report of the first successful case. JAMA 112:729,1939.Google Scholar
  11. 11.
    Hosking MCK, Benson LN, Musewe N, Dyck JD, Freedom RM: Transcatheter occlusion of the persistently patent ductus arteriosus: forty-month follow-up and prevalence of residual shunting. Circulation 84:2313,1991.PubMedGoogle Scholar
  12. 12.
    Jones JC: Twenty-five years’ experience with surgery of patent ductus arteriosus. J Thorac Cardiovasc Surg 50:149,1965.PubMedGoogle Scholar
  13. 13.
    Keys A, Shapiro MJ: Patency of the ductus arteriosus in adults. Am Heart J 25: 158,1943.CrossRefGoogle Scholar
  14. 14.
    Kirklin JW, Silver AW: Technique of exposing the ductus arteriosus prior to establishing extracorporeal circulation. Mayo Clin Proc 33:423,1958.Google Scholar
  15. 15.
    Lam CR: A safe technique for closure of the recurrent patent ductus arteriosus. J Thorac Cardiovasc Surg 72:232,1976.PubMedGoogle Scholar
  16. 16.
    Latson LA: Residual shunts after transcatheter closure of patent ductus arteriosus: a major concern or benign “techno-malady”? (editorial) Circulation 84:2591,1991.PubMedGoogle Scholar
  17. 17.
    Levitsky S, Fisher E, Vidyasagar D, Hastreiter AR, Bennett EJ, Raju TNK, Roger K: Interruption of patent ductus arteriosus in premature infants with respiratory distress syndrome. Ann Thorac Surg 22:131,1976.PubMedCrossRefGoogle Scholar
  18. 18.
    Liao PK, Su WJ, Hung JS: Doppler echocardiographic flow characteristics of isolated patent ductus arteriosus: better delineation by doppler color flow mapping. J Am Coll Cardiol 12:1285,1988.PubMedCrossRefGoogle Scholar
  19. 19.
    Morrow AG, Clark WD: Closure of calcified patent ductus arteriosus: a new operative method utilizing cardiopulmonary bypass. J Thorac Cardiovasc Surg 51: 534,1964.Google Scholar
  20. 20.
    O’Donovan TG, Beck W: Closure of the complicated patent ductus arteriosus. Ann Thorac Surg 25:464,1978.Google Scholar
  21. 21.
    Panagopoulos PG, Tatooles CJ, Aberdeen E, et al: Patent ductus arteriosus in infants and children. A review of 936 operations. Thorax 26:137,1971.PubMedCrossRefGoogle Scholar
  22. 22.
    Pifarre R, Rice PL, Nemickas R: Surgical treatment of calcified patent ductus arteriosus. J Thorac Cardiovasc Surg 65:625,1973.Google Scholar
  23. 23.
    Rashkind WJ, Mullins CE, Hellenbrand WE, Tait MA: Nonsurgical closure of patent ductus arteriosus: clinical application of the Rashkind PDA Occluder System. Circulation 75:583,1987.PubMedCrossRefGoogle Scholar
  24. 24.
    Rudolph AM: Congenital Diseases of the Heart. Chicago, Year Book, 1974.Google Scholar
  25. 25.
    Silverman NH, Lewis AB, Heymann MA, et al: Echocardiographic assessment of ductus arteriosus shunt in premature infants. Circulation 50:821,1974.PubMedGoogle Scholar
  26. 26.
    Swensson RE, Valdes-Cruz LM, Sahn DJ, Sherman FS, Chung KJ, Scagnelli S, Hagen-Ansert S: Real-time doppler color flow mapping for detection of patent ductus arteriosus. J Am Coll Cardiol 8:1105,1986.PubMedCrossRefGoogle Scholar
  27. 27.
    USCI/Bard: Personal communication. 1993.Google Scholar
  28. 28.
    Wessel DL, Keane JF, Parness I, Lock JE: Outpatient closure of the patent ductus arteriosus. Circulation 77:1068,1988.PubMedCrossRefGoogle Scholar
  29. 29.
    Williams WH, Gelband H, Boncalari E, Bauer C, Garcia O, Tamer D, Kaiser GA: The ductus debate: ligation in prematurity? Ann Thorac Surg 22:151,1976.PubMedCrossRefGoogle Scholar
  30. 30.
    Yeh TF, Luken JA, Thalji A, Raval D, Carr I, Pildes RS: Intravenous indomethacin therapy in premature infants with persistent ductus arteriosus—a double-blind controlled study. J Pediat 98:137,1981.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York, Inc. 1995

Authors and Affiliations

  • Bradley J. Harlan
    • 1
    • 2
    • 3
  • Albert Starr
    • 3
    • 4
    • 5
  • Fredic M. Harwin
    • 6
  • Alain Carpentier
    • 7
  1. 1.Section of Thoracic and Cardiovascular SurgerySutter Memorial HospitalSacramentoUSA
  2. 2.Davis Medical SchoolUniversity of CaliforniaSacramentoUSA
  3. 3.Oregon Health Sciences UniversityPortlandUSA
  4. 4.Heart Institute at St. Vincent HospitalPortlandUSA
  5. 5.Starr-Wood Cardiac Group, P.C.PortlandUSA
  6. 6.Harwin StudiosPortlandUSA
  7. 7.Hôpital BroussaisUniversity of ParisParisFrance

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