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Introduction to Bioorganic Chemistry

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Bioorganic Chemistry

Part of the book series: Springer Advanced Texts in Chemistry ((SATC))

Abstract

Among the first persons to develop biooriented organic projects was F.H. Westheimer, in the 1950s. He was probably the first physical organic chemist to do serious studies of biochemical reactions. However, it was only twenty years later that the field blossomed to what is now accepted as bioorganic chemistry.

It might be helpful to remind ourselves regularly of the sizeable incompleteness of our understanding, not only of ourselves as individuals and as a group, but also of Nature and the world around us.” N. Hackerman Science 183, 907 (1974)

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References

  1. V.B. Schatz (1960), Isosterism and bio-isosterism as guides to structural variations. In: Medicinal Chemistry (A. Burger, Ed.), 2nd ed., pp. 72–88. Interscience, New York.

    Google Scholar 

  2. A. Korolkovas (1970), Essentials of Molecular Pharmacology, pp. 55–59. Wiley-Interscience, New York.

    Google Scholar 

  3. G.I. Birnbaum, M. Cygler, and D. Shugar (1984), Conformational features of acyclonucleotides: structure of acyclovir, an antiherpes agent. Can. J. Chem. 62, 2646–2652.

    Article  CAS  Google Scholar 

  4. R. Engel (1979), Phosphonates as analogues of natural phosphates. Chem. Rev. 77, 349–367.

    Article  Google Scholar 

  5. K.C. Tang, B.E. Tropp, and R. Engel (1978), The synthesis of phosphonic acid and phosphate analogues of glycerol-3-phosphate and related metabolites. Tetrahedron 34, 2873–2878.

    Article  CAS  Google Scholar 

  6. E. Frieden (1981), Iodine and the thyroid hormones. Trends Biochem. Sci. 6, 50–53.

    Article  CAS  Google Scholar 

  7. T.P. Singer, A.J. Trevor, and N. Castagnoli, Jr. (1987), Biochemistry of the neurotoxic action of MPTP. Trends Biochem. Sci. 12, 266–270.

    Article  CAS  Google Scholar 

  8. J.-M. Lehn (1985), Supramolecular chemistry: Receptors, catalysts, and carriers. Science 227, 849–850.

    Article  CAS  Google Scholar 

  9. H. Colquhoun, F. Stoddart, and D. Williams (1986), Chemistry beyond the molecules. New Scientist, May 1, p. 44.

    Google Scholar 

  10. K.L. Wolf, M. Duken, and K. Merkel (1940), Über Übermolekülbildung. Z. Phys. Chem. Abt. B 46, 287–312.

    Google Scholar 

  11. J.M. Lehn (1993), Supramolecular chemistry—molecular information and the design of supramolecular materials. Makromol. Chem. Macromol. Symp. 69, 1–17.

    Article  CAS  Google Scholar 

  12. C.J. Suckling, K.E. Suckling, and C.W. Suckling (1979), Chemistry Through Models. Cambridge University Press, Cambridge.

    Google Scholar 

  13. S. Sasaki, M. Shionoya, and K. Koga (1985), Functionalized crown ether as an approach to the enzyme model for the syntheses of peptides. J. Am. Chem. Soc. 107, 3371–3372.

    Article  CAS  Google Scholar 

  14. B.A. Boyce, A. Carroy, J.-M. Lehn, and D. Parker (1984), Heterotopic ligands: Synthesis and complexation properties of phosphine-functionalized dipodal macrocycles. Chem. Commun. 1546–1548.

    Google Scholar 

  15. T.R. Cech (1987), The chemistry of self-splicing RNA and DNA enzymes. Science 236, 1532–1539.

    Article  CAS  Google Scholar 

  16. T.R. Cech (1986), RNA as an enzyme. Sci. Amer. Dec., pp. 64–75.

    Google Scholar 

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© 1996 Springer-Verlag New York, Inc.

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Dugas, H. (1996). Introduction to Bioorganic Chemistry. In: Bioorganic Chemistry. Springer Advanced Texts in Chemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2426-6_1

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  • DOI: https://doi.org/10.1007/978-1-4612-2426-6_1

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-98910-5

  • Online ISBN: 978-1-4612-2426-6

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