Testis-Specific Gene Transcription

  • Kourosh Salehi-Ashtiani
  • Erwin Goldberg
Part of the Serono Symposia USA Norwell, Massachusetts book series (SERONOSYMP)


The classic studies of Monesi (1,2) in the 1960s revealed an intricate pattern of RNA synthesis during spermatogenesis, characterized by transient transcriptional activity. During the early stages of meiotic prophase, a relatively low rate of [3H]uridine incorporation was detected; however, RNA synthesis increases at the mid-pachytene stage followed by diminution during the meiotic divisions. RNA synthesis once again increases in the round and elongating spermatids (up to step 8), followed by a decline in later stages where nuclear condensation occurs.


Transition Protein Mouse Testis Translational Regulation Meiotic Prophase Phosphoglycerate Kinase 
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Copyright information

© Springer-Verlag New York, Inc. 1996

Authors and Affiliations

  • Kourosh Salehi-Ashtiani
  • Erwin Goldberg

There are no affiliations available

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