Skip to main content
SpringerLink
Log in

Introduction

Causality of Hormone-Associated Human Cancers

  • Conference paper
Hormonal Carcinogenesis II

  • 60 Accesses

Abstract

Early epidemiologic studies linked reproductive and hormonal factors to breast cancer risk (1). These factors included early age at menarche, natural age at menopause, menstrual characteristics, nulliparity, age at first full-term pregnancy, number of live births, and lactation. A woman’s family history of breast cancer has also been known for quite some time to affect breast cancer risk strongly (2).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Kelsey JL, Gammon MD, John EM (1993) Reproductive factors and breast cancer. Epidemiol Rev 15:36–47.

    PubMed  CAS  Google Scholar 

  2. Macklin MT (1959) Comparison of the number of breast cancer deaths observed in relatives of breast cancer patients, and the number expected on the basis of mortality rates. J Natl Cancer Inst 22:927–951.

    PubMed  CAS  Google Scholar 

  3. Hunter DJ, Willett WC (1993) Diet, body size, and breast cancer. Epidemiol Reviews 15:110–132.

    CAS  Google Scholar 

  4. Malone KE, Daling JR, Weiss NS (1993) Oral contraceptives and breast cancer risk. Epidemiol Rev 15:80–97.

    PubMed  CAS  Google Scholar 

  5. Brinton LA, Schairer C (1993) Estrogen replacement therapy and breast cancer risk. Epidemiol Rev 15:66–79.

    PubMed  CAS  Google Scholar 

  6. White E, Malone KE, Weiss NS, Daling JR (1994) Breast cancer among young U.S. women in relation to oral contraceptive use. J Natl Cancer Inst 86:505–514.

    Article  PubMed  CAS  Google Scholar 

  7. Stanford JL, Thomas DT (1993) Exogenous progestins and breast cancer. Epidemiol Rev 15:98–107.

    PubMed  CAS  Google Scholar 

  8. Rosenberg L, Metzger LS, Palmer JR (1993) Alcohol consumption and risk of breast cancer: A review of the epidemiologic evidence. Epidemiol Rev 15:133–144.

    PubMed  CAS  Google Scholar 

  9. Gammon MD, John EM (1993) Recent etiologic hypotheses concerning breast cancer. Epidemiol Rev 15:163–168.

    PubMed  CAS  Google Scholar 

  10. Frisch RE, Wyshak G, Albright NL et al (1985) Lower prevalence of breast cancer and cancers of the reproductive system among former college athletes compared to non-athletes. Br J Cancer 52:885–891.

    Article  PubMed  CAS  Google Scholar 

  11. Vihko JV, Apter DL, Pukkala EI et al (1992) Risk of breast cancer among female teachers of physical education and languages. Acta Oncol 31:201–204.

    Article  PubMed  CAS  Google Scholar 

  12. Bernstein L, Henderson BE, Hanisch R et al (1994) Physical exercise and reduced risk of breast cancer in young women. J Natl Cancer Inst 86:1403–1408.

    Article  PubMed  CAS  Google Scholar 

  13. Dorgan JF, Brown C, Barrett M et al (1994) Physical activity and risk of breast cancer in the Framingham Heart Study. Am J Epidemiol 139:662–669.

    PubMed  CAS  Google Scholar 

  14. Daling JR, Malone KE, Voigt LF et al (1994) Risk of breast cancer among young women: Relationship to induced abortion. J Natl Cancer Inst 86:1584–1592.

    Article  PubMed  CAS  Google Scholar 

  15. Lip worth L, Katsouyanni K, Ekbom A et al (1995) Abortion and the risk of breast cancer. A case-control study in Greece. Int J Epidemiol, in press.

    Google Scholar 

  16. Rookus MA, van Leeuwen FE (1995) Breast cancer risk after induced abortion, a Dutch case-control study. Am J Epidemiol 141: S54.

    Google Scholar 

  17. Bu L, Boigt LF, Yu Z et al (1995) Risk of breast cancer associated with induced abortion in a population at low risk of breast cancer. Am J Epidemiol 141:S85.

    Google Scholar 

  18. Newcomb PA, Storer BE, Longnecker MP et al (1995) Pregnancy termination in relation to risk of breast cancer. Am J Epidemiol 141: S54.

    Google Scholar 

  19. Russo J, Russo IH (1987) Biology of disease. Biological and molecular bases of mammary carcinogenesis. Lab Invest 57:112–137.

    PubMed  CAS  Google Scholar 

  20. Russo J, Wilgus G, Russo IH (1979) Susceptibility of the mammary gland to carcinogenesis. I. Differentiation of the mammary gland as determinant of tumor incidence and type of lesion. Am J Pathol 96:721–736.

    PubMed  CAS  Google Scholar 

  21. Miki Y, Swensen J, Shattuck-Eidens D et al (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266:66–71.

    Article  PubMed  CAS  Google Scholar 

  22. Wooster R, Neuhausen SL, Mangion J et al (1994) Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13ql2–13. Science 265:2088–2090.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. Janet R. Daling
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Division of Etiology and Prevention of Hormonal Cancers, Hormonal Carcinogenesis Laboratory, University of Kansas Cancer Center, Kansas City, Kansas, USA

    J. Jonathan Li Ph.D. (Professor of Pharmacology, Toxicology, and Therapeutics, Director) (Professor of Pharmacology, Toxicology, and Therapeutics, Director)

  2. Hormonal Carcinogenesis Laboratory, University of Kansas Cancer Center, Kansas City, Kansas, USA

    Sara Antonia Li Ph.D. (Associate Professor of Pharmacology, Toxicology, and Therapeutics) (Associate Professor of Pharmacology, Toxicology, and Therapeutics)

  3. Department of Medical Nutrition, Center for Biotechnology, NOVUM, Huddinge University Hospital, Huddinge, Sweden

    Jan-Åke Gustafsson M.D., Ph.D. (Professor and Chairman, Director) (Professor and Chairman, Director)

  4. Department of Molecular and Cell Biology, Cancer Research Center, University of California, Berkeley, California, USA

    Satyabrata Nandi Ph.D. (Professor of Cell and Development Biology) (Professor of Cell and Development Biology)

  5. Division of Cancer Etiology, Chemical and Physical Carcinogenesis Program, National Cancer Institute, Rockville, Maryland, USA

    Lea I. Sekely Ph.D. (Program Director) (Program Director)

  6. University of Kansas Medical Center, Kansas City, Kansas, USA

    J. Jonathan Li Ph.D. (Professor of Pharmacology, Toxicology, and Therapeutics, Director) & Sara Antonia Li Ph.D. (Associate Professor of Pharmacology, Toxicology, and Therapeutics) (Professor of Pharmacology, Toxicology, and Therapeutics, Director) &  (Associate Professor of Pharmacology, Toxicology, and Therapeutics)

  7. National Institutes of Health, Rockville, Maryland, USA

    Lea I. Sekely Ph.D. (Program Director) (Program Director)

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer-Verlag New York, Inc.

About this paper

Cite this paper

Daling, J.R. (1996). Introduction. In: Li, J.J., Li, S.A., Gustafsson, JÅ., Nandi, S., Sekely, L.I. (eds) Hormonal Carcinogenesis II. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2332-0_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-2332-0_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7506-0

  • Online ISBN: 978-1-4612-2332-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation