A Cell Cycle Regulator and Cancer

  • Alexander C. Kamb
Conference paper


During cell division, eukaryotic cells execute a basic set of steps referred to as the cell cycle (1). The cell cycle consists of 4 general time periods, or phases: G1, during which the cell grows and prepares for DNA synthesis; S, during which DNA replication occurs; G2, during which the cell continues to grow and prepares for mitosis; and M, during which cytokinesis occurs. The vast majority of cells in most tissue compartments are not continuously dividing, but rather in a resting state known as G0. When the appropriate stimulus is received, G0 - arrested cells enter the cell cycle.


Cell Cycle Tumor Suppressor Gene Esophageal Squamous Cell Carcinoma Cell Cycle Regulator Homozygous Deletion 
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© Springer-Verlag New York, Inc. 1996

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  • Alexander C. Kamb

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