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Regulation of Prostate Growth and Gene Expression: Role of Stroma

  • Leland W. K. Chung
  • Chuan Gao
  • Haiyen E. Zhau
Conference paper

Abstract

Cellular interaction is recognized as a continuing event, essential in multicellular organisms for acquiring preprogrammed structure and assuming differentiated functions. Aberrant cellular interaction could create misguided signals between cells, resulting in developmental defects and unregulated growth control in both vertebrate and invertebrate organisms. Examples found in the mammalian species are the mosaic Tfm/y mice, which produced offspring that might inherit regional developmental defects of their reproductive organs (1). Reactivation of the inductive potential of embryonic mesenchymes in the adult prostate gland was proposed as one underlying mechanism for the histogenesis of benign prostatic hyperplasia (2).

Keywords

LNCaP Cell Human Prostate Cancer Prostate Growth Genomic Adaptation Soluble Growth Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York, Inc. 1996

Authors and Affiliations

  • Leland W. K. Chung
  • Chuan Gao
  • Haiyen E. Zhau

There are no affiliations available

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