Regulation of Growth-Associated Nuclear Transcription Factors During Growth Hormone-Regulated, Sex-Differentiated Rat Liver Carcinogenesis

  • Inger Porsch Hällström
  • DeZhong Liao
  • Lena Ohlson
  • Agneta Blanck
Conference paper


The incidence of hepatocellular carcinoma (HCC) in man is markedly sex differentiated, with a higher frequency in men than in women, in both high-risk and low-incidence areas (1, 2). Furthermore, both androgens and synthetic estrogens are potential risk factors for liver cancer (3, 4). Also, the induction of liver tumors in experimental animals is often sex differentiated, and both gonadal and pituitary hormones play an important role in this process (5–7).


Growth Hormone Treatment Proto Oncogene Focal Growth Persistent Nodule Male Lesion 
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Copyright information

© Springer-Verlag New York, Inc. 1996

Authors and Affiliations

  • Inger Porsch Hällström
  • DeZhong Liao
  • Lena Ohlson
  • Agneta Blanck

There are no affiliations available

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