Abstract
The ability to understand developmental processes requires appropriate organisms. The field of genetics established the precedent of focusing research on a few reference or “model” organisms such as Drosophila or maize. Recent developmental biology has depended on a small number of organisms for much of its spectacular progress. This concentration of effort facilitates attempts to advance in the analysis of the basic processes down to the molecular level. On the other hand, there is no single organism that could be selected to study all fundamental events and aspects of development because each developmental pattern leads to a particular species and not to a generalized animal. From the egg of Drosophila, a fruit fly arises, not an insect in general, not a fish, and not a human being. General principles are only recognized when the events of development are studied in several diverse organisms, which develop differently yet display some common features. In addition, laboratory work quickly reveals that even the best model organism exhibits, in addition to its particular advantages, specific disadvantages. Thus the zebra fish has transparent embryos, but large-scale genetic studies require hundreds of aquariums and a staff of workers, and the fruit fly has a wealth of developmental mutants but cannot be conveniently frozen for long-term storage.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliography
Thomson, J.A., and Solter, D. (1989): The developmental fate of androgenetica, parthenogenetic, and gynogenetic cells in chimeric gastrulating mouse embryos. Genes Dev. 2:1344–1351.
Wagner, E.F., and Keller, G. (1992): The introduction of genes into mouse embryos and stem cells. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 440–458. Springer-Verlag, Heidelberg.
Wischnitzer, S. (1975): Atlas and Laboratory Guide for Vertebrate Embryology. McGraw-Hill, New York.
Sea Urchin
Billet, F.S., and Wild, A.E. (1975): Practical Studies of Animal Development, Echinoderms and Ascidians. Chapman & Hall, London.
Czihak, G. (1975): The Sea Urchin Embryo. Springer-Verlag, Heidelberg.
Davidson, E.H. (1989): Lineage specific gene expression and the regulative capacities of the sea urchin embryo: A proposed mechanism. Development 105:421–445.
Hardin, J. (1994): The sea urchin. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 37–53. Wolfe, London.
Hörstadius, S. (1973): Experimental Embryology of Echinoderms. Clarendon Press, Oxford.
Whitaker, M., and Swann, K. (1993): Lighting the fuse at fertilization. Development 117:1–12.
Dictyostelium
Bozzaro, S. (1992): Dictyostelium: From unicellularity to multicellularity. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 137–149. Springer-Verlag, Heidelberg.
Brookman, J.J., Jermyn, K.A., and Kay, R.R. (1987): Nature and distribution of the morphogen DIF in the Dictyostelium slug. Development 100: 119–124.
Kay, R.R., Berks, M., and Traynor, D. (1989): Morphogen hunting in Dictyostelium. Development (Suppl.):81–90.
Kay, R., and Insall, R. (1994): Dictyostelium discoideum. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 23–35. Wolfe, London.
Konijin, T.M., van der Meene, J.G.C., Bonner, J.T., and Barkley, D. (1967): The acrasin activity of adenosine-3′, 5′-cyclic phosphate. Proc. Natl. Acad. Sci. USA 58:1152–1154.
Loomis, W.F. (1975): Dictyostelium discoideum. A Developmental System. Academic Press, New York.
Ohmori, T., and Maeda, Y. (1987): The developmental fate of Dictyostelium discoideum cells depends greatly on the cell-cycle position at the onset of starvation. Cell Differ. 22:11–18.
Oohata, A.A. (1995): Factors controlling prespore cell differentation in Dictyostelium discoideum: Minute amounts of differentation-inducing factor promote prespore cell differentiation. Differentiation 59:283–288.
Schaap, P. (1991): Intercellular interactions during Dictyostelium development. In Dworkin, M. (ed.) Microbial Cell-Cell Interactions, pp. 147–178. American Society for Microbiology, Washington, D.C.
Takeuchi, I., Tosaka, M., Okamoto, K., and Maeda, Y. (1994): Regulation of cell differentiation and pattern formation in Dictyostelium development. Int. J. Dev. Biol. 38:311–319.
Weijer, C.J., Duschl, G., and David, C.N. (1984): Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum. Exp. Cell Res. 70:133–145.
Hydra and Other Hydrozoa
Berking, S. (1986): Transmethylation and control of pattern formation in hydrozoa. Differentiation 32:10–16.
Bode, P.M., and Bode, H.R. (1984): Patterning in Hydra. In Malacinski, G.M., and Bryant, S.V. (eds.) Pattern Formation, Vol. I, pp. 213–241, Macmillan, New York.
Gierer, A. (1977): Biological features and physical concepts of pattern formation exemplified by Hydra. In Moscona, A.A., and Monroy, A. (eds.) Pattern Development. CurrTop. Dev. Biol. 11:17–58.
Lange, R.G., Müller, W.A. (1991): SIF, a novel morphogenetic inducer in hydrozoa. Dev. Biol. 11:17–58.
Müller, W.A. (1975): Hydractinia echinata. Ablaichen, Embryonalentwicklung, Metamorphose. Film E2080 mit Begleittext. Institut für Wissenschaftlichen Film, Göttingen, Germany.
Müller, W.A. (1995): Competition for factors and cellular resources as a principle of pattern formation in Hydra. Dev. Biol. 167:159–174 (Part I);
Müller, W.A. (1995): Competition for factors and cellular resources as a principle of pattern formation in Hydra. Dev. Biol. 167:175–189 (Part II).
Müller, W.A. (1996): Pattern formation in the immortal Hydra. Trends Genet. 11:91–96
Caenorhabditis elegans
Bossinger, O., and Schierenberg, E. (1992): Cell-cell communication in the embryo of Caenorhabditis elegans. Dev. Biol. 151:401–409.
Boveri, T. (1904 and 1910): See Bibliography for Box 1.
Brenner, S. (1974): The genetics of Caenorhabditis elegans. Genetics 77: 71–94.
Edgar, L. (1992): Embryogenesis in Caenorhabditis elegans. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 273–294. Springer-Verlag, Heidelberg.
Hope, I.A. (1994): 4. Caenorhabditis elegans In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 55–75. Wolfe, London.
Ruvkun, G. (1992): Generation of temporal and cell lineage asymmetry during C. elegans development. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 295–307. Springer-Verlag, Berlin.
Schierenberg, E. (1982): Development of the nematode Caenorhabditis elegans. In Developmental Biology of Freshwater Invertebrates, pp. 249–281. Alan R. Liss, New York.
Spiralians
Anderson, D.T. (1973): Embryology and Phylogeny in Annelids and Arthropods. Pergamon Press, Oxford.
Atkinson, J.W. (1987): An arias of light micrographs of normal and lobe-less larvae of the marine gastropood Ilyanassa obsoleta. Int. J. Invert. Reprod. Dev. 9:169–178.
Biggelaar, J.A.M., van den, Dictus, W.J.A.G., and Serras, E. (1994): Molluscs. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 77–91. Wolfe, London.
de Laat, S.W., et al. (1980): Intercellular communication patterns are involved in cell determination in early molluscan development. Nature (London) 287:546–548.
Dorrestejin, A., et al. (1993): Molecular specification of cell lines in the embryo of Platynereis (Annelida). Roux’s Arch. Dev. Biol. 202:260–269.
Freeman, G., and Lundelius, J.W. (1982): The developmental genetics of dextrality and sinistrality in the gastropod Lymnea peregra. Roux’s Arch. Dev. Biol. 191:69–83.
Gourrier, P., et al. (1978): Significance of the polar lobe for the determination of dorsoventral polarity in Dentalium vulgare (da Costa). Dev. Biol. 53: 233–242.
Harrison, W., and Cowden, R.R. (1982): Developmental Biology of Freshwater Invertebrates. Alan R. Liss, New York.
Raven, C.R (1966): Morphogenesis: The Analysis of Molluscan Development. Pergamon Press, Oxford.
Reverberi, G. (1971): Experimental embryology of marine and freshwater invertebrates. North-Holland Publishing Co., Amsterdam.
Weisblat, D.A. (1994): The leech. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 93–112. Wolfe, London.
Drosophila
Beachy, P.A. (1990): A molecular view of the Ultrabithorax homeotic gene of Drosophila. Trends Genet. 6(2):46–51.
Campos-Ortega, J.A., and Hartenstein, V. (1996): Embryonic Development of Drosophila melanogaster. 2nd ed. Springer-Verlag, Heidelberg.
Campos-Ortega, J.A., and Knust, E. (1992): Genetic mechanisms in early neurogenesis of Drosophila melanogaster. In Russo, V., et al. (eds.) Development: The Molecular Genetic Approach, pp. 341–354. Springer-Verlag, Heidelberg.
Driever, W., and Nüsslein-Volhard, C. (1988): The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54:95–104.
Driever, W., Siegel, V., and Nüsslein-Volhard, C. (1990): Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen. Development 109:811–820.
Govind, S., and Steward, R. (1991): Dorsoventral pattern formation in Drosophila. Trends Genet. 7:119–124.
Heemskerk, J., et al. (1994): Drosophila hedgehog acts as a morphogen in cellular patterning. Cell 76:449–460.
Lawrence, P.A. (1992). The Making of a Fly. The Genetics of Animal Design. Blackwell Scientific, Oxford.
Leptin, M. (1994): Drosophila. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 113–134. Wolfe, London.
Micklem, D.R. (1995): mRNA localisation during development. Dev. Biol. 172:377–395.
Rongo, C., and Lehmann, R. (1996): Regulated synthesis, transport and assembly of the Drosophila germ plasm. Trends Genet. 12:102–109.
St. Johnston D., and Nüsslein-Volhard, C. (1992): The origin of pattern and polarity in the Drosophila embryo. Cell 68:201–219.
Struhl, G. (1981): A homeotic mutation transforming leg to antenna in Drosophila. Nature (London) 292:635–638.
Struhl, G., Strahl, K., and Macdonald, P.M. (1989): The gradient morphogen bicoid is a concentration-dependent transcriptional activator. Cell 57:1259–1273.
Tautz, D. (1992): Genetic and molecular analysis of early pattern formation in Drosophila. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 308–327. Springer-Verlag, Heidelberg.
Tunicates
Bates, W.R., and Jeffery, W.R. (1987): Localization of axial determinants in the vegetal pole region of ascidian eggs. Dev. Biol. 124:65–76.
Conklin, E.G. (1905): Mosaic development in ascidian eggs. J. Exp. Zool. 2:145–223.
Jeffery, W.R. (1990): An ultraviolet-sensitive maternal mRNA encoding a cytoskeletal protein may be involved in axis formation in the ascidian embryo. Dev. Biol. 141:141–148.
Meedel, T.H., Crowthier, R.J., and Wittaker, J.R. (1987): Determinative properties of muscle lineages in ascidian embryos. Development 100:245–260.
Nishida, H. (1990): Determinative mechanisms in secondary muscle lineages of ascidian embryos: Development of muscle-specific features in isolated muscle progenitor cells. Development 108:559–568.
Nishida, H. (1992): Developmental potential for tissue differentiation of fully dissociated cells of the ascidian embryo. Roux’s Arch. Dev. Biol. 201: 81–87.
Sardet, C., et al. (1989): Fertilization and ooplasmic movements in the ascidian egg. Development 105:237–249.
Whittaker, J.R. (1979): Cytoplasmic determinants of tissue differentiation in the ascidian egg. In Subtelny, S., and Konigsberg, I.R. (eds.) Determinants of Spatial Organization, pp. 29–51. Academic Press, New York.
Whittaker, J.R. (1980): Acetylcholinesterase development in extra cells caused by changing the distribution of myoplasm in ascidian embryos. J. Embryol. Exp. Morphol. 55:343–354.
Whittaker, J.R. (1987): Cell lineages and determinants of cell fate in development. Am. Zool. 27:607–622.
Xenopus, Amphibians
Billet, F.S., and Wild, A.E. (1975): Practical Studies of Animal Development, Amphibians. Chapman & Hall, London.
Bolce, M.E., et al. (1992): Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin. Development 115:681–688.
Cho, K.W.Y., et al. (1991): Molecular nature of Spemann’s organizer: The role of the Xenopus Homeobox gene goosecoid. Cell 67:1111–1120.
Chui, Y., et al. (1995): Xwnt-8b: A maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis. Development 121: 2177–2186.
Dohrmann, C.E., et al. (1993): Expression of activin mRNA during early development in Xenopus laevis. Development 157:474–483.
Gerhart, J., et al. (1981): A reinvestigation of the role of the grey crescent in axis formation in Xenopus laevis. Nature 292:511–516.
Gerhart, J., et al. (1986): Amphibian early development. BioScience 36: 541–549.
Gilbert, S.F., Saxén. L. (1993): Spemann’s organizer: Models and molecules. Mech. Dev. 41:73–89.
Grunz, H. (1993): The dorsalization of Spemann’s organizer takes place during gastrulation in Xenopus laevis embryos. Dev. Growth Differ. 35(1):25–32.
Grunz, H., Schüren C., and Richter, K. (1995): The role of vertical and planar signals during the early steps of neural induction. Int. J. Dev. Biol. 39: 539–543.
Gurdon, J.B. (1987): Embryonic induction—molecular prospects. Development 99:285–306.
Gurdon, J.B., et al. (1994): Activin signalling and response to a morphogen gradient. Nature 371:487–492.
Hausen, P., and Riebesoll, M. (1991): The Early Development of Xenopus laevis. Springer-Verlag, Heidelberg.
Hemmati-Brivaniou, A., Kelly, O.G., and Melton, D.A. (1994): Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neutralizing activity. Cell 77:283–295.
Hemmati-Brivaniou, A., and Melton, D.A. (1994): Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77:273–281.
Henry, J.J., and Grainger, R.M. (1990): Early tissue interactions leading to embryonic lens formation in Xenopus laevis. Dev. Biol. 141:149–163.
Jacobson, A.G. (1994): Normal neurulation in amphibia. In Bock, G., and Marsh, J. (eds.) Neural Tube Defects, pp. 49–65. John Wiley & Sons, New York.
Keller, R.E. (1986): The cellular basis of amphibian gastrulation. In Browder, L. (ed.) Developmental Biology: A Comprehensive Synthesis. Vol. 2, pp. 241–327. Plenum, New York.
Kessler, D.S., and Melton, D.A. (1995): Induction of dorsal mesoderm by soluble, mature Vgl protein. Development 121:2155–2164.
Kimelman, D., et al. (1992): Synergistic principles of development: Overlapping patterning systems in Xenopus mesoderm induction. Development 116: 1–9.
Micklem, D.R. (1995): mRNA localisation during development. Dev. Biol. 172:377–395.
Niehrs, C., et al. (1993): The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72:491–503.
Niehrs, C., Steinbeisser, H., and De Robertis, E.M. (1994): Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science 263:817–820.
Nieuwkoop, P.D. (1977): Origin and establishment of embryonic polar axes in amphibian development. In Moscona, A.A., and Monroy, A. (eds.) Pattern Development. Curr. Top. Dev. Biol. 11:115–132.
Nieuwkoop, P.D., and Faber, J. (1975): Normal Table of Xenopus laevis (Daudin), 2nd ed., North-Holland Publishing Co., Amsterdam.
Otte, A.P., et al. (1988): Protein kinase C mediates neural induction in Xenopus laevis. Nature 334:618–620.
Pieler, T. (1992): Xenopus embryogenesis. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 355–369. Springer-Verlag, Heidelberg.
Rugh, R. (1962): Experimental Embryology. Burgess, Minneapolis.
Sasai, Y., et al. (1994): Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79:779–790.
Sasai, Y., et al. (1995): Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signal in Xenopus. Nature 376:333.
Sive, H.L. (1993): The frog prince-ss: A molecular formula for dorsoventral patterning in Xenopus. Genes Dev. 7:1–12.
Slack, J.M.W. (1993): Embryonic induction. Mech. Dev. 41:91–107.
Slack, J.M.W. (1994): Xenopus. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 149–166. Wolfe, London.
Smith, W.C., and Harland, R.M. (1992): Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70:829–840.
Smith, W.C., et al. (1993): Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361:547–549.
Sokol, S.Y, and Melton, D.A. (1992): Interaction of wnt and activin in dorsal mesoderm induction in Xenopus. Dev. Biol. 154:348–355.
Sosoi, Y., et al. (1994): Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79:779–790.
Steinbeisser, H., et al. (1993): Xenopus axis formation: Induction of goosecoid by injected WXwnt-8 and activin mRNAs. Development 118:499–507.
Vincent, J.P., and Gerhart, J.C. (1987): Subcortical rotation in Xenopus eggs: An early step in embryonic axis formation. Dev. Biol. 123:526–529.
Wischnitzer, S. (1975): Atlas and Laboratory Guide for Vertebrate Embryology. McGraw-Hill, New York.
Danio (formerly Brachydanio, Zebra Fish)
Hisaoka, K.K., and Battle, H.I. (1985): The normal developmental stages of the zebrafish Brachydanio rerio (Hamilton-Buchanan). J. Morphol. 102: 311–328.
Laale, H.W. (1977): The biology and use of zebrafish, Brachydanio rerio in fisheries research. J. Fish Biol. 10:121–173.
Metcalfe, W.K. (1994): The zebrafish. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 135–147. Wolfe, London.
Rugh, R. (1962): Experimental Embryology. Burgess, Minneapolis.
Strähle, U., and Ingham, P.W. (1992): Zebrafish development: Flight of fancy or a major new school? Curr. Biol. 2:135–139.
Warga, R.M., and Kimmel, C.B. (1990): Cell movements during epiboly and gastrulation in zebrafish. Development 108:569–580.
Woo, K., and Fraser, S.E. (1995): Order and coherence in the fate map of the zebrafish nervous system. Development 121:2595–2609.
Bird
Billet, F.S., and Wild, A.E. (1975): Practical Studies of Animal Development, Birds. Chapman & Hall, London.
Patten, B.M. (1951): Early Embryology of the Chick. 5th ed. McGraw-Hill, New York.
Romanoff, A.L. (1960): The Avian Embryo. Macmillan, New York.
Rugh, R. (1962): Experimental Embryology. Burgess, Minneapolis.
Stern, C.D. (1994): The chick. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 167–182. Wolfe, London.
Stern, C.D., and Canning, D.R. (1990): Origin of cells giving rise to mesoderm and endoderm in chick embryo. Nature 343:273–275.
Wischnitzer, S. (1975): Atlas and laboratory guide for vertebrate embryology. McGraw-Hill, New York.
Mouse
Bard, J.B.L., and Kaufmann, M.H. (1994): The mouse. In Bard, J.B.L. (ed.) Embryos, Color Atlas of Development, pp. 183–206. Wolfe, London.
Barlow, D.P. (1992): Cloning developmental mutants from the mouse t complex. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 394—408. Springer-Verlag, Heidelberg.
Billet, F.S., and Wild, A.E. (1975): Practical Studies of Animal Development, Mammals. Chapman & Hall, London.
Bürki, K. (1986): Experimental Embryology of the Mouse. S. Karger, Basel.
Hogan, B., Constantini, F., and Lacy, E. (1986): Manipulating the Mouse Embryo. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
Lobe, C.G., and Gruss, P. (1992): From Drosophila to mouse. In Russo, V.E.A., et al. (eds.) Development: The Molecular Genetic Approach, pp. 382–393. Springer-Verlag, Heidelberg.
Rugh, R. (1967): Experimental Embryology. Burgess, Minneapolis.
Surani, M.A.H., Barton, S.C., and Norris, M.L. (1986): Nuclear transplantation in the mouse: Hereditable differences between parental genomes after activation of the embryonic genome. Cell 45:127–136.
Theiler, K. (1989): The House Mouse. Atlas of Embryonic Development. 2nd printing. Springer-Verlag, Heidelberg.
Human
England, M.A. (1994): The human (by M. England). In Bard, J.B.L. (ed) Embryos, Color Atlas of Development, pp. 207–220. Wolfe, London.
Hinrichsen, K.V (1990): Human Embryology. Springer-Verlag, Heidelberg.
Langman, J. (1989): Medical Embryology. The Williams & Wilkins Co., Baltimore.
Moore, K.L. (1990): Grundlagen der medizinischen Embryologie. Enke, Stuttgart, Germany.
Tuchmann-Duplessis, H., David, G., and Haegel, P. (1972): Illustrated Human Embryology. Vol. 1 and 2. Springer-Verlag, New York.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer-Verlag New York, Inc.
About this chapter
Cite this chapter
Müller, W.A. (1997). Model Organisms in Developmental Biology. In: Developmental Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2248-4_3
Download citation
DOI: https://doi.org/10.1007/978-1-4612-2248-4_3
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-7472-8
Online ISBN: 978-1-4612-2248-4
eBook Packages: Springer Book Archive