A Generalized Mathematical Theory of the Multiple-Indicator Dilution Method
Tracer techniques have proven to be invaluable for the quantitative assessment of metabolic and biological transport processes. The multiple-indicator dilution technique as a special form of a tracer method is particularly suitable for the study of relatively rapid processes occurring in intact organs. In the previous chapters, the principles and some important applications of the multiple-indicator dilution technique have been addressed. In this chapter, a more detailed analysis of the mathematical foundations of this technique will be presented. This allows us to put this technique in a more general framework of tracer analysis, yielding a systematic approach to finding numerical solutions that apply in a more general way, whereas the analytical solutions presented in Chapter 13 are applicable only in simpler cases.
KeywordsTransfer Coefficient Laplace Transformation Indicator Dilution Compartmental System Laguerre Function
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