Role of Sonography in Patients with Breast Cancer

  • Bruno D. Fornage
Part of the M.D. Anderson Solid Tumor Oncology Series book series (MDA)


With the state-of-the-art equipment currently available, sonography (US) of the breast has become an essential complement to physical examination and mammography, not only to differentiate cystic from solid masses but to characterize the solid masses and differentiate benign from malignant tumors. US has changed the approach to the “indeterminate breast mass.” It has also emerged as the optimal guidance technique for percutaneous interventional procedures (e.g., biopsy or localization) involving nonpalpable breast masses.


Breast Cancer Needle Biopsy Invasive Lobular Carcinoma Breast Masse Granular Cell Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Gui GP, Allum WH, Perry NM, et al. One-stop diagnosis for symptomatic breast disease. Ann R Coll Surg 1995;77:24–27.Google Scholar
  2. 2.
    Fornage BD. Ultrasound of the breast. Ultrasound Q 1993;11:1–39.CrossRefGoogle Scholar
  3. 3.
    Weng L, Tirumalai AP, Lowery CM, et al. US extended-field-of-view imaging technology. Radiology 1997;203:877–880.PubMedGoogle Scholar
  4. 4.
    Fornage BD, Lorigan JG, Andry E. Sonographic appearance of fibroadenoma of the breast. Radiology 1989;172:671–675.PubMedGoogle Scholar
  5. 5.
    Rissanen T, Typpö T, Tikkakoski T, et al. Ultrasound-guided percutaneous galactography. J Clin Ultrasound 1993;21:497–502.PubMedCrossRefGoogle Scholar
  6. 6.
    Fornage BD, Faroux MJ, Pluot M, et al. Nipple adenoma simulating carcinoma: misleading clinical, mammographic, sonographic, and cytologic findings. J Ultrasound Med 1991;10:55–57.PubMedGoogle Scholar
  7. 7.
    Stavros AT, Thickman D, Rapp CL, et al. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196:123–134.PubMedGoogle Scholar
  8. 8.
    Paramagul CP, Helvie MA, Adler DD. Invasive lobular carcinoma: sonographic appearance and role of sonography in improving diagnostic sensitivity. Radiology 1995;195:231–234.PubMedGoogle Scholar
  9. 9.
    Chopra S, Evans AJ, Pinder SE, et al. Pure mucinous breast cancer—mammographic and ultrasound findings. Clin Radiol 1996;51:421–424.PubMedCrossRefGoogle Scholar
  10. 10.
    Samuels TH, Miller NA, Manchul LA, et al. Squamous cell carcinoma of the breast. Can Assoc Radiol J 1996;47:177–182.PubMedGoogle Scholar
  11. 11.
    Ambrogetti D, Ciatto S, Catarzi S, et al. The combined diagnosis of male breast lesions: a review of a series of 748 consecutive cases. Radiol Med (Torino) 1996;91:356–359 (in Italian).Google Scholar
  12. 12.
    Carlson GW, Curley SA, Martin JE, et al. The detection of breast cancer after augmentation mammaplasty. Plast Reconstr Surg 1993;91:837–840.PubMedCrossRefGoogle Scholar
  13. 13.
    Meterissian S, Fornage BD, Singletary SE. Clinically occult breast carcinoma: diagnostic approaches and role of axillary node dissection. Ann Surg Oncol 1995;2:314–318.PubMedCrossRefGoogle Scholar
  14. 14.
    Peters-Engl C, Medl M, Leodolter S. The use of colour-coded and spectral Doppler ultrasound in the differentiation of benign and malignant breast lesions. Br J Cancer 1995;71:137–139.PubMedCrossRefGoogle Scholar
  15. 15.
    Kedar RP, Cosgrove D, McCready VR, et al. Microbubble contrast agent for color Doppler US: effect on breast masses; work in progress. Radiology 1996;198:679–686.PubMedGoogle Scholar
  16. 16.
    Madjar H, Prompeler HJ, Sauerbrei W, et al. Differential diagnosis of breast lesions by color Doppler. Ultrasound Obstet Gynecol 1995;6:199–204.PubMedCrossRefGoogle Scholar
  17. 17.
    Youssefzadeh S, Eibenberger K, Helbich T, et al. Use of resistance index for the diagnosis of breast tumours. Clin Radiol 1996;51:418–420.PubMedCrossRefGoogle Scholar
  18. 18.
    Fornage BD. Role of color Doppler imaging in differentiating between pseudocystic malignant tumors and fluid collections. J Ultrasound Med 1995;14:125–128.PubMedGoogle Scholar
  19. 19.
    Fornage BD, Faroux MJ, Simatos A. Breast masses: US-guided fine-needle aspiration biopsy. Radiology 1987;147:409–414.Google Scholar
  20. 20.
    Fornage BD, Sneige N, Faroux MJ, et al. Sonographic appearance and ultrasound-guided fine-needle aspiration biopsy of breast carcinomas smaller than 1 cm3. J Ultrasound Med 1990;9:559–568.PubMedGoogle Scholar
  21. 21.
    Fornage BD. Percutaneous biopsies of the breast: state of the art. Cardiovasc Intervent Radiol 1991;14:29–39.PubMedCrossRefGoogle Scholar
  22. 22.
    Fornage BD, Coan JD, David CL. Ultrasound-guided needle biopsy of the breast and other interventional procedures. Radiol Clin North Am 1992;30:167–185.PubMedGoogle Scholar
  23. 23.
    Gordon PB, Goldenberg SL, Chan NHL. Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy. Radiology 1993;189:573–580.PubMedGoogle Scholar
  24. 24.
    Parker SH, Jobe WE, Dennis MA, et al. US-guided automated large-core breast biopsy. Radiology 1993;187:507–511.PubMedGoogle Scholar
  25. 25.
    Fornage BD. Interventional ultrasound of the breast. In: McGahan J, (ed) Interventional Ultrasound. Baltimore: Williams & Wilkins, 1989;71–83.Google Scholar
  26. 26.
    Fornage BD. Ultrasound-guided percutaneous needle biopsy of nonpalpable breast masses. In: Harris JR, Lippman ME, Morrow M, Hellman S (eds) Diseases of the Breast. Philadelphia: Lippincott-Raven, 1996;152–158.Google Scholar
  27. 27.
    Sneige N, Fornage BD, Saleh G. Ultrasound-guided fine-needle aspiration of nonpalpable breast lesions: cytologic and histologic findings. Am J Clin Pathol 1994;102:98–101.PubMedGoogle Scholar
  28. 28.
    Lundy J, Lozowski M, Sadri D, et al. The use of fine-needle aspirates of breast cancers to evaluate hormone-receptor status. Arch Surg 1990;125:174–176.PubMedGoogle Scholar
  29. 29.
    Fischler DF, Sneige N, Ordonez NG, et al. Tubular carcinoma of the breast: cytologic features in fine-needle aspirations and application of monoclonal anti a-smooth muscle actin in diagnosis. Diagn Cytopathol 1994;10:120–125.PubMedCrossRefGoogle Scholar
  30. 30.
    Kline TS, Joshi LP, Neal HS. Fine-needle aspiration of the breast: diagnoses and pitfalls; a review of 3545 cases. Cancer 1979;44:1458–1464.PubMedCrossRefGoogle Scholar
  31. 31.
    Peterse JL, Thunnissen FB, van Heerde P. Fine needle aspiration cytology of radiation-induced changes in nonneoplastic breast lesions: possible pitfalls in cytodiagnosis. Acta Cytol 1989;33:176–180.PubMedGoogle Scholar
  32. 32.
    Fornage BD. US-guided core needle biopsy of breast masses: the “bayonet artifact” [letter]. AJR Am J Roentgenol 1995;164:1022–1023.PubMedGoogle Scholar
  33. 33.
    Kaplan SS, Racenstein MJ, Wong WS, et al. US-guided core biopsy of the breast with a coaxial system. Radiology 1995;194:573–575.PubMedGoogle Scholar
  34. 34.
    Fornage BD, Sneige N, Singletary SE. Masses in breasts with implants: diagnosis with US-guided fine-needle aspiration biopsy. Radiology 1994;191:339–342.PubMedGoogle Scholar
  35. 35.
    Schackmuth M, Harlow CL, Norton LW. Milk fistula: a complication after core breast biopsy. AJR Am J Roentgenol 1993;161:961–962.PubMedGoogle Scholar
  36. 36.
    Harter LP, Swengros J, Ponto G, et al. Malignant seeding of the needle track during stereotaxic core needle breast biopsy. Radiology 1992;185:713–714.PubMedGoogle Scholar
  37. 37.
    Harlow CL, Schackmuth EM, Bregman PS, et al. Sonographic detection of hematomas and fluid after imaging guided core breast biopsy. J Ultrasound Med 1994;13:877–882.PubMedGoogle Scholar
  38. 38.
    Ciatto S, Catarzi S, Morrone D, et al. Fine-needle aspiration cytology of nonpalpable breast lesions: US versus stereotaxic guidance. Radiology 1993;188:195–198.PubMedGoogle Scholar
  39. 39.
    Fornage BD. A simple phantom for training in ultrasound-guided needle biopsy using the freehand technique. J Ultrasound Med 1989;8:701–703.PubMedGoogle Scholar
  40. 40.
    Fornage BD, Toubas O, Morel M. Clinical, mammographic and sonographic determination of preoperative breast cancer size. Cancer 1987;60:765–771.PubMedCrossRefGoogle Scholar
  41. 41.
    Meden H, Neues KP, Roben-Kampken S, et al. A clinical, mammographic, sonographic and histologic evaluation of breast cancer. Int J Gynaecol Obstet 1995;48:193–199.PubMedCrossRefGoogle Scholar
  42. 42.
    Yang WT, Ahuja A, Tang A, et al. Ultrasonographic demonstration of normal axillary lymph nodes: a learning curve. J Ultrasound Med 1995;14:823–827.PubMedGoogle Scholar
  43. 43.
    Pamilo M, Soiva M, Lavast E-M. Real-time ultrasound, axillary mammography, and clinical examination in the detection of axillary lymph node metastases in breast cancer patients. J Ultrasound Med 1989;8:115–120.PubMedGoogle Scholar
  44. 44.
    Glynne-Jones R, Makepeace AR, Spittle MF, et al. A possible role for ultrasound of the axilla in staging primary breast cancer. Clin Oncol (R Coll Radiol) 1990;2:35–38.Google Scholar
  45. 45.
    Oran I, Memis A, Ustun EE. Ultrasonographic detection of interpectoral (Rotter’s) node involvement in breast cancer. J Clin Ultrasound 1996;24:519–522.PubMedCrossRefGoogle Scholar
  46. 46.
    Tschammler A, Ott G, Kumpflein P, et al. Differentiation of malignant from reactive lymphadenopathy using color Doppler flow imaging. J Ultrasound Med 1996;15 (suppl):S76.Google Scholar
  47. 47.
    Bruneton JN, Caramella E, Héry M, et al. Axillary lymph node metastases in breast cancer: preoperative detection with US. Radiology 1986;158:325–326.PubMedGoogle Scholar
  48. 48.
    Mustonen P, Farin P, Kosunen O. Ultrasonographic detection of metastatic axillary lymph nodes in breast cancer. Ann Chir Gynaecol 1990;79:15–18.PubMedGoogle Scholar
  49. 49.
    Tate JJ, Lewis V, Archer T, et al. Ultrasound detection of axillary lymph node metastases in breast cancer. Eur J Surg Oncol 1989;15:139–141.PubMedGoogle Scholar
  50. 50.
    Scatarige JC, Hamper UM, Sheth S, et al. Parasternal sonography of the internal mammary vessels: technique, normal anatomy, and lymphadenopathy. Radiology 1989;172:453–457.PubMedGoogle Scholar
  51. 51.
    Ozdemir H, Atilla S, Ilgit ET, et al. Parasternal sonography of the internal mammary lymphatics in breast cancer: CT correlation. Eur J Radiol 1995;19:114–117.PubMedCrossRefGoogle Scholar
  52. 52.
    Fornage BD, Ross MI, Singletary SE, et al. Localization of impalpable breast masses: value of sonography in the operative room and scanning of excised specimens. AJR Am J Roentgenol 1994;163:569–573.PubMedGoogle Scholar
  53. 53.
    Schwartz GF, Goldberg BB, Rifkin MD, et al. Ultrasonography: an alternative to x-ray-guided needle localization of nonpalpable breast masses. Surgery 1988;104:870–873.PubMedGoogle Scholar
  54. 54.
    Fornage BD, Samuels BI, Paulus DD, et al. The use of sonography in the evaluation of the response of locally advanced breast carcinoma to preoperative chemotherapy [abstract]. J Ultrasound Med 1990;9:23.Google Scholar
  55. 55.
    Gawne-Cain ML, Smith E, Darby M, et al. The use of ultrasound for monitoring breast tumour response to pro-adjuvant therapy. Clin Radiol 1995;50:681–686.PubMedCrossRefGoogle Scholar
  56. 56.
    Edeiken-Monroe BS, Fornage BD, Holmes FA. A preliminary report of sonographically guided implantation of metallic markers to permanently localize the tumor bed in patients with breast cancer receiving preoperative chemotherapy. Presented at the 97th Annual Meeting of the American Roentgen Ray Society, Boston, May 4–9, 1997.Google Scholar

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© Springer-Verlag New York, Inc. 1999

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  • Bruno D. Fornage

There are no affiliations available

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