Abstract
Population studies have repeatedly shown a beneficial effect of postmenopausal estrogen (E) use on coronary heart disease (CHD) (1), with an overall reduction of around 50% in the incidence. Prospective randomized controlled clinical trials are now under way to confirm these epidemiological findings (2). However, it is clearly important to understand the biological basis of these actions of E on the cardiovascular (CV) system in order to optimize current hormone replacement therapies (HRT) and develop new HRT with maximum CV impact for the future.
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Stevenson, J.C. (2001). Mechanisms of Estrogen Action on the Cardiovascular System. In: Li, J.J., Li, S.A., Daling, J.R. (eds) Hormonal Carcinogenesis III. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2092-3_36
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DOI: https://doi.org/10.1007/978-1-4612-2092-3_36
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