Abstract
Perhaps one of the most unique early hormonal events in estrogen (E) oncogenesis is the elicitation of genomic instability as a consequence of estrogen receptor (ER-α)-mediated cell proliferation. The focus of the studies presented herein is to provide evidence for this contention, and for a multi-stage sequence of events leading to tumor development, employing the Syrian hamster E-induced and -dependent renal neoplasm model.
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Li, J.J., Weroha, S.J., Cansler, M., Li, S.A. (2001). Estrogen Receptor-mediated Genomic Instability in the Syrian Hamster Kidney: A Critical Event in Hormonal Oncogenesis. In: Li, J.J., Li, S.A., Daling, J.R. (eds) Hormonal Carcinogenesis III. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2092-3_14
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DOI: https://doi.org/10.1007/978-1-4612-2092-3_14
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-7411-7
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