The Isolated Organ in Research

  • T. YehJr.
  • A. S. Wechsler

Abstract

Technological advances in artificial perfusion allow effective isolated perfusion of a wide variety of organs and tissues, including, but not limited to, brain, heart, lung, heart-lung, liver, kidney, spleen, pancreas, thymus, gastrointestinal tract, urinary tract, reproductive tract, skeletal muscle, nerves, and blood vessels. The option of extended pharmacological or surgical treatment of animals before organ isolation makes this technique extremely powerful. To the uninitiated, isolated organ perfusion may conjure up images of Frankensteinian surgery, machinery, and complexity; however, surgeons are particularly well equipped to implement these models, which actually are much simpler today than they were historically.

Keywords

Cellulose Hydration Rubber Syringe Fractionation 

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • T. YehJr.
  • A. S. Wechsler

There are no affiliations available

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