Premature Ejaculation

  • Allen D. Seftel
  • Stanley E. Althof


Traditionally, the etiology of premature ejaculation, a prevalent male dysfunction, was believed to be psychological and was treated therefore with a variety of behavioral or other psychotherapeutic techniques. Pharmacotherapy for treatment of premature ejaculation is presently in its infancy; however, it offers urologists an additional option for medical management of this distressing condition.


Erectile Dysfunction Sexual Dysfunction Premature Ejaculation Ejaculatory Latency Psychotherapeutic Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994.Google Scholar
  2. 2.
    Halvorsen J, Metz M. Sexual dysfunction. Part 1: classification, etiology, and pathogenesis. J Am Board Fam Pract 1992; 5: 51–61.PubMedGoogle Scholar
  3. 3.
    Kaplan H. Overcoming Premature Ejaculation. New York: Bruner-Mazel; 1989.Google Scholar
  4. 4.
    Levine S. Sexual Life: A Clinicians Guide. New York: Plenum; 1992.Google Scholar
  5. 5.
    LoPiccolo J, LoPiccolo L. Handbook of Sex Therapy. New York: Plenum; 1978.CrossRefGoogle Scholar
  6. 6.
    McCarthy B. Cognitive-behavioral strategies and techniques in the treatment of early ejaculation. In: Leiblum SR, Rosen R, eds. Principles and Practice of Sex Therapy: Update for the 90’s. New York: Guilford; 1990.Google Scholar
  7. 7.
    Masters W, Johnson V. Human Sexual Inadequacy. Boston: Little, Brown; 1970.Google Scholar
  8. 8.
    St. Lawrence J, Madakasira S. Evaluation and treatment of premature ejaculation: a critical review. Int J Psych 1992; 22:77–97.CrossRefGoogle Scholar
  9. 9.
    Semans J. Premature ejaculation: a new approach. South Med J 1956; 49: 353–358.PubMedCrossRefGoogle Scholar
  10. 10.
    Hawton K, Catalan J. Prognostic factors in sex therapy. Behav Res Ther 1986; 24: 377–385.PubMedCrossRefGoogle Scholar
  11. 11.
    Bancroft J, Coles L. Three years experience in a sexual problems clinic. Br Med J 1976; 1: 1575 1577.Google Scholar
  12. 12.
    DeAmicus L, Goldberg D, LoPiccolo J, et al. Clinical follow-up of couples treated for sexual dysfunction. Arch Sex Behav 1985; 14: 467–489.CrossRefGoogle Scholar
  13. 13.
    Assalian P. Clomipramine in the treatment of premature ejaculation. J Sex Res 1988; 24: 231–251.CrossRefGoogle Scholar
  14. 14.
    Goodman. RE. An assessment of clomipramine (Anafranil) in the treatment of premature ejaculation. J Intern Med Res 1980; 8 (suppl3): 53–59.Google Scholar
  15. 15.
    Segraves RT, Saran S, Segraves K, et al. Clomipramine versus placebo in the treatment of premature ejaculation: a pilot study. J Sex Marital Ther 1993; 19: 198–200.PubMedCrossRefGoogle Scholar
  16. 16.
    Kaplan P. The use of serotonergic uptake inhibitors in the treatment of premature ejaculation. J Sex Marital Ther 1995; 20: 321–324.CrossRefGoogle Scholar
  17. 17.
    Waldinger M, Hengeveld M, Zwinderman A. Paroxetine treatment of premature ejaculation: a double-blind randomized placebo-controlled study. Am J Psychiatry 1994; 151: 1377–1379.PubMedGoogle Scholar
  18. 18.
    Althof S, Levine S, Corty E, et al. Clomipramine as a treatment for rapid ejaculation: a double-blind crossover trial of fifteen couples. J Clin Psychiatry (in press).Google Scholar
  19. 19.
    Althof S, Resnick K, Levine S, et al. Early experience with clomipramine for rapid ejaculation. Paper presented to the Annual Meeting of the American Urological Association, Las Vegas, Nevada, 1995.Google Scholar
  20. 20.
    Maier U, Koinig G. Andrological findings in young patients under long-term antidepressive therapy with clomipramine Psychopharmacology 1994; 116: 357–359.PubMedCrossRefGoogle Scholar
  21. 21.
    Mendels J, Camera A, Sikes C. Sertraline treatment for premature ejaculation. J Clin Psychopharmacol 1995; 15: 341–346.PubMedCrossRefGoogle Scholar
  22. 22.
    Swartz D. Sertraline hydrochloride for premature ejaculation [abstract 471]. In: Programs and Abstracts of the 89th Annual Meeting of the American Urological Association, San Francisco, CA, 1994: 345A.Google Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Allen D. Seftel
  • Stanley E. Althof

There are no affiliations available

Personalised recommendations