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Squamous Cell Carcinoma of the Uterine Cervix

  • Dennis W. Ross
Chapter

Abstract

“Squamous cell carcinoma of the uterine cervix is caused by a virus and may be cured by a vaccine.” To be more precise, let me rephrase that to say: Human papilloma virus (HPV) is a common initiating factor in the cascade of molecular events that leads to squamous cell carcinoma of the cervix. A vaccine that impedes HPV should decrease the incidence of cervical cancer. This chapter discusses viral carcinogenesis. We will find that host factors affecting HPV infection modulate the likelihood of cancer. Again, we will prove the maxim that cancer develops in multiple steps over a period of years.

Keywords

Squamous Cell Carcinoma Cervical Cancer Human Papilloma Virus Uterine Cervix Human Papilloma Virus Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Barbosa MS. The oncogenic role of human papillomavirus proteins. Critical Reviews in Oncogenesis. 1996;7:1–18.PubMedCrossRefGoogle Scholar
  2. Demay R. The Art and Science of Cytopathology. Exfoliative Cytology. Chicago: ASCP Press, 1996:97–108Google Scholar
  3. Prasad CJ. Pathobiology of human papillomavirus. Clin Lab Med. 1995;15:685–704.PubMedGoogle Scholar
  4. Shroyer KR, Thompson LC, Enomoto T, et al. Telomerase expression in normal epithelium, reactive atypia, squamous dysplasia, and squamous cell carcinoma of the uterine cervix. Am J Clin Pathol. 1998;109:153–162.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Dennis W. Ross
    • 1
  1. 1.Department of PathologyForsyth Medical CenterWinston-SalemUSA

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