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Molecular diagnostics seeks to detect errors that cause disease at the level of DNA. This is a rapidly evolving field with new technologies leapfrogging over previous methods. Unthinkable only a few years ago, now the most direct method of examining DNA is sequencing by automated methods. This chapter discusses the clinical laboratory tools available and probable near future developments. Surprisingly, I think that I will soon make apparent to you that our molecular technology is already well developed. Where we are stuck is limited clinical experience. Molecular diagnostics can detect disease at a level that we are only now ready to address. The major breakthroughs in molecular diagnostics await physicians discovering the correct use of the technology.
KeywordsChronic Myeloid Leukemia Phase Fraction Molecular Diagnostics Image Cytometry Base Pair Sequence
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