Neonatal Vitamin Metabolism: Fat Soluble

  • Frank R. Greer
  • Richard D. Zachman


The fat-soluble vitamins are an exciting area of perinatal research. The nutrient-gene interaction of vitamin A is perhaps the best described of any nutrient and we are continually learning more about its important role in fetal development. Vitamin D, actually a prohormone, is not far behind in the description of its effects on DNA transcription and its impact on fetal development is one of growing importance. New vitamin K—dependent proteins, other than coagulation factors, are being described in many organ tissues and knowledge of vitamin K’s role in perinatal metabolism is expanding. Of all the fat-soluble vitamins, vitamin E has the most proposed therapeutic benefits in the perinatal period. However, there are still no definite indications for its routine clinical use in pharmacologic quantities.


Bronchopulmonary Dysplasia Other Hand Premature Neonate Retinyl Palmitate Maternal Vitamin 
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© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Frank R. Greer
  • Richard D. Zachman

There are no affiliations available

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