Cell Loss During Spermatogenesis: Apoptosis or Necrosis?

  • Lonnie D. Russell
Part of the Serono Symposia USA book series (SERONOSYMP)


Spermatogenesis is the process by which stem cell spermatogonia form sperm. In theory, one stem cell spermatogonium of the rat can produce 4096 sperm (1). The theoretical limit is never achieved in normal spermatogenesis because cells degenerate along the way. Numerous genetic, environmental, and toxicological factors can negatively influence the yield of cells. Although several papers and reviews have been written on this topic (2–5), the relatively recent description of apoptosis has prompted this author to revisit the topic.


Germ Cell Sertoli Cell Cell Degeneration Male Germ Cell Round Spermatid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 1999

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  • Lonnie D. Russell

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