Optimization of Conductivity and Permeability Parameters for Brain, CSF, Skull and Scalp Using Implanted Sources in the Human Cranium
By invoking the dipole in a sphere model, researchers elude the volume current effects in MagnetoEncephaloGraphic (MEG) localizations . The drive for better accuracy, however, has led to the Boundary Element Model (BEM)  which more closely represents head and brain anatomy. The drawback, of course, is that volume currents are not suppressed in a BEM as they are in the dipole in a sphere model. Proper account of the volume current in the BEM requires the macroscopic conductivities associated with the four major head tissue layers: brain, CerebroSpinal Fluid (CSF), skull, and scalp. Unfortunately, prior studies to determine these parameters [3–5] have never been confirmed in the context of MEG localization studies.
KeywordsPermeability Parameter Dipole Location Boundary Element Model Signal Template Macroscopic Conductivity
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