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Ischemia and Reperfusion as a Cause of Multiple Organ Failure

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Multiple Organ Failure

Abstract

Multiple organ failure continues to be the most common cause of late death after injury. It is also one of the most common causes of mortality in the intensive care unit after major catastrophic medical illnesses and surgical complications. The pathogenesis of the syndrome remains incompletely understood, but it is most likely related to some combination of a dysregulated inflammatory response, maldistribution of microcirculatory blood flow, ischemia-reperfusion injury, and deregulation of immune function.

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Authors
  1. H. Gill Cryer
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Editor information

Editors and Affiliations

  1. Department of Surgery, St. Louis University Hospital, St. Louis, Missouri, 63110, USA

    Arthur E. Baue MD (Professor Emeritus) (Professor Emeritus)

  2. Department of Surgery, Klinikum Grosshadern, University of Munich, Munich, D-81377, Germany

    Eugen Faist MD (Professor) (Professor)

  3. Department of Surgery, School of Medicine, University of New Mexico, Albuquerque, New Mexico, 87131, USA

    Donald E. Fry MD (Professor and Chairman) (Professor and Chairman)

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© 2000 Springer Science+Business Media New York

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Cryer, H.G. (2000). Ischemia and Reperfusion as a Cause of Multiple Organ Failure. In: Baue, A.E., Faist, E., Fry, D.E. (eds) Multiple Organ Failure. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1222-5_12

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  • DOI: https://doi.org/10.1007/978-1-4612-1222-5_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7049-2

  • Online ISBN: 978-1-4612-1222-5

  • eBook Packages: Springer Book Archive

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