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Polymer Solutions and Films as Tissue-Protective and Barrier Adjuvants

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Peritoneal Surgery

Abstract

This chapter is primarily devoted to a discussion of two very different concepts for development of polymeric compositions designed to inhibit postoperative adhesion formation in all types of surgery. One concept, which has received the least attention and which we therefore consider in more detail, is that of tissue protection during surgery by the use of polymer solutions as tissue coatings intended to minimize manipulative and desiccation trauma in the surgical field. The second concept, which has been the primary focus of research in this field for the past 20 years, is that of barrier coatings or films designed to be placed, at the end of surgery, over tissues that have been damaged during surgery. Such coatings or films may thereby act as barriers to the bridging of apposite damaged tissues with unwanted internal scar tissue (adhesions).

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Authors
  1. Lynn S. Peck
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  2. Eugene P. Goldberg
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Editors and Affiliations

  1. Livingston Research Institute, University of Southern California School of Medicine, 1321 N. Mission Rd., Los Angeles, California, 90033, USA

    Gere S. diZerega M.D. (Professor of Obstetrics and Gynecology) (Professor of Obstetrics and Gynecology)

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Peck, L.S., Goldberg, E.P. (2000). Polymer Solutions and Films as Tissue-Protective and Barrier Adjuvants. In: diZerega, G.S. (eds) Peritoneal Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1194-5_41

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  • DOI: https://doi.org/10.1007/978-1-4612-1194-5_41

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