Pathology pp 1-12 | Cite as

Principles of Cell/Tissue Injury

  • John H. Holliman
Part of the Oklahoma Notes book series (OKLAHOMA)


The viability of a cell is dependent on its ability to produce energy, to manufacture essential proteins, to maintain its structural integrity and, in most cases, to replicate. Interference with any of these functions can affect the entire cell and may be reflected by structural, biochemical, or molecular changes within the cell which may ultimately be expressed as clinical signs and symptoms of “disease”. “Health”, therefore, depends on the ability of cells to maintain structural and functional stability (a steady state) in the face of a constantly changing microenvironment, a process termed homeostasis.


Glycogen Storage Disease Acute Poisoning Mature Cell Type Lipid Storage Disease Dermal Appendage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • John H. Holliman
    • 1
  1. 1.Department of Pathology College of Medicine Health Sciences CenteThe University of OklahomaOklahoma CityUSA

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