Basic Aspects of Cystic Fibrosis

  • Jeffrey J. Wine
Part of the Allergy and Immunology book series (ALIM, volume 1)

Abstract

Cystic fibrosis (CF) is manifestly a disease of the exocrine organs (1) to which the respiratory, digestive, and reproductive tracts are hereby included as honorary members. In years past, few individuals with CF survived infancy. Up to 10% of affected children died shortly after birth as a result of complications from meconium ileus, and survivors, who were typically malnourished, usually succumbed to repeated and persistent lung infections. These problems can now be ameliorated, but the underlying defect remains (Fig. 1).

Keywords

Permeability Pseudomonas Cytosol Acetylcholine Phenylalanine 

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Jeffrey J. Wine
    • 1
  1. 1.Cystic Fibrosis Research Laboratory, Building 420, Jordan Hall, Stanford UniversityStanfordUSA

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