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Fluorine Concentrations in Bone Biopsy Samples Determined by Proton-Induced Gamma-Ray Emission and Cyclic Neutron Activation

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Nuclear Analytical Methods in the Life Sciences

Abstract

Fluorine concentrations in bone biopsy samples taken from the iliac crest of subjects, divided Into four groups depending on the length of dialysis treatment, and aluminium levels In blood and bone pathology, In terms of osteoporosis, were determined by two Instrumental methods. Proton-induced gamma-ray emission (PIGE), making use of the resonance reaction of 19F(p,αγ)16O at 872 keV, and cyclic neutron activation analysis (CNAA), using the 19F(n,γ)20F reaction in a reactor irradiation facility, were employed. Rutherford back- scattering (RBS) was used to calculate the volume, and, hence, mass of the sample excited In PIGE by determining the major element composition of the samples In order to express results In terms of concentration. From this preliminary Investigation, a relationship is suggested between fluorine concentrations In bone and aluminium levels in the system.

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© 1990 Springer Science+Business Media New York

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Spyrou, N.M. et al. (1990). Fluorine Concentrations in Bone Biopsy Samples Determined by Proton-Induced Gamma-Ray Emission and Cyclic Neutron Activation. In: Zeisler, R., Guinn, V.P. (eds) Nuclear Analytical Methods in the Life Sciences. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0473-2_18

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  • DOI: https://doi.org/10.1007/978-1-4612-0473-2_18

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6777-5

  • Online ISBN: 978-1-4612-0473-2

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