Abstract
The management of connective-tissue diseases, such as systemic lupus erythematosus (SLE), can often be as daunting as the disease itself. The prospect of early cardiovascular disease, diabetes, obesity, and aseptic necrosis as a consequence of long-term corticoste- roid therapy is overshadowed only by the possibility of sterility and/ or neoplasia resulting from the immunosuppressive agents we have in use today. New therapies must be found, and recent reports have suggested that intravenous immune serum globulin (IVIG) may be an option (1–4).
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Corvetta, A., Delia Bitta, R., Gabrielli, A., Spaeth, P. J., and Danieli, G. (1989), Clin. Exp. Rheumatol. 7, 295–299.
Akashi, K, Nagasawa, K., Mayumi, T., Yokota, E., Oochi, N., and Kusaba, T. (1990), J. Rheumatol. 17,375–379.
Silverman, E. D., Laxer, R. M., Greenwald, M., Gelfand, E., Shore, A., Stein, L. D., and Roifman, C. M. (1990), Arthritis Rheum. 33, 1015–1022.
Leung, D. Y. M. (1989), J. Allergy Clin. Immunol. 84, 588–594.
Boey, M. L., Colaco, C. B., Gharavi, A. E., Eklon, K. B., Loizou, S., and Hughes, G. R. V. (1983), BMJ 287, 1021–1023.
Edelman, P. H. G., Rouquette, A. M., Verdy, E., Elias, A., Cabane, J., Cornet, D., Barrât, J., Chavinie, J., Salat-Baroux, J., and Sureau, Cl. (1986), Human Repro. 1,295–297.
Harris, E. N., Gharavi, A. E., Asherson, R. A., Boey, M. L., and Hughes, G. R. V. (1984), Clin. Exp. Rheum. 2, 247–251.
Unander, A. M., Norberg, R., Hahn, L., and Årfors, L. (1987), Am. J. Obstet. Gynecol. 156,114–119.
Freyssinet, J. and Cazenave, J. (1987), Throm. Haem. 58, 679–681.
Marciniak, E. and Romond, E. H. (1989), Blood 74, 2426–2432.
Bussel, J. B., Schulman, I., Hilgartner, M. W., and Barandun, S. (1983), J. Pediatr. 103,651–654.
Mori, P. G., Mancuso, G., Del Principe, D., et al: (1983), Arch. Dis. Child. 58,851–855.
Newland, A. C, Terleaven, J. G., Minchinton, R. M., and Waters, A. H. (1983), Lancet 1, 84–87.
Bussell, J. B., Goldman, A., Imbach, P., Schulman, I., and Hilgartner, M. W. (1985), J. Pediatr. 106,886–890.
Ball, S., Zuiable, A., Roter, B. L. T., and Hegde, U. M. (1985), Br. J. Haema-tol. 60, 631–633.
Nydeger, U. E. and Spycher, M. O. (1986), Clinical Use of Intravenous Immunoglobulins (Morrell, A. and Nydegger, U. E., eds.), Academic Press, London, pp. 431–441.
Bussell, J., Pahwa, S., Porges, A., Cunningham-Rundles, S., Koziner, B., Morell, A., and Barandun, S. (1986), J. Clin. Immunol. 6, 50–56.
Imbach, P., Barandun, S., D’Apuzzo, V., Baumgartner, C, Hirt, A., Morell, A., Rossi, E., Scholini, M., Vest, M., and Wagner, H. P. (1981), Lancet 1, 1228–1231.
Fehr, J., Hoffman, V., and Kappeier, U. (1982), N. Engl. J. Med. 306,1254–1258.
Ballow, M., White, W., and Desbonnet, C. (1989), J. Allergy Clin. Immunol. 84,595–602.
Jordan, S. C. (1989), Clin. Immunol. Immunopathol. 53, S164–S169.
Ballow, M. and Parke, A. (1989), J. Allergy Clin. Immunol. 84, 608–612.
Newburger, J. W., Takahashi, M., Burns, J. C, et al: (1986), N. Engl. J. Med. 315, 341–347.
DeWolf, F., Carreras, L. O., Moerman, P., Vermylen, J., Van Assche, A., and Renaer, M. (1982), Am. J. Obstet. Gynecol. 142,829–834.
Nilsson, I. M., Astedt, B., Hedner, U., and Berezin, D. (1975), Acta Med. Scand. 197,153–159.
Lesperance, B., David, M., Rauch, J., Infante-Rivard, C, and Rivard, G. E. (1988), Thromb. Hemost. 60, 217–219.
Harris, E. N. (1990), Am. J Clin. Pathol. 94, 476–484.
Lockshin, M. D., Druzin, M. L., Goei, S., Qamar, T., Magid, M. S., Jovanovic, L., and Ferenc, M. (1985), N. Engl. J. Med. 313,152–156.
Maier, D. B. and Parke, A. L. (1989), Fertil. Steril. 51,280–285.
Parke, A. L., Wilson, D., and Maier, D. The prevalence of antiphospholipid antibodies in habitual aborters, normal mothers and in women who have never been pregnant. (A & R, in press.)
Parke, A. L., Maier, D., Hakim, C, Randolph, J., and Andreoli, J. (1986), J. Rheumatol. 13,1178–1180.
Stafford-Brady, F. J., Gladman, D. D., and Urowitz, M. B. (1988), Arch. Intern. Med. 148, 1647,1648.
Lubbe, W. F., Palmer, S. J., Butler, W. S., and Liggins, G. C. (1983), Lancet 1,1361–1363.
Branch, W. B., Scott, J. R., Kochenour, N. K, and Hershgold, E. (1985), N. Engl. J. Med. 313,1322–1321.
Walport, M. (1989), Ann. Rheum. Dis. 48, 795–797.
McNeil, H. P., Chesterman, C. N., and Krilis, S. A. (1989), Br. J. Hematol. 73,506–513.
McVerry, B. A., Spearing, R., and Smith, A. (1985), Br. J. Haematol. 61, 579,580.
Carreras, L. O., Perez, G. N., Vega, H. R., and Casavilla, F. (1988), Lancet 2, 393,394.
Scott, J. R., Branch, D. W., Kochenour, N. K, and Ward, K. (1988), Am. J. Obstet. Gynecol. 159, 1055,1056.
Francois, A., Freund, M., Daffos, F., Remy, P., and Jacquot, C. (1988), Ann. Int. Med. 109, 993,994.
Parke, A., Maier, D., Wilson, D., Andreoli, J., and Ballow, M. (1989), Ann. Int. Med. 110, 495,496.
Wapner, R. J., Cowchock, F. S., and Shapiro, S. S. (1989), Am. J. Obstet. Gynecol. 161, 1271,1272.
Katz, V. L., Thorp, J. M., Watson, W. J., Fowler, L., and Heine, R. P. H. (1981), Obstet. Gynecol. 58, 430–434.
MacLachlan, N. A., Letsky, E., DeSwiet, M., and Rodeck, C. H. (1990), Clin. Exp. Rheumatol. 8, 221.
Rosove, M. H., Tabsh, K, Wasserstrum, N., Howard, P., Hahn, B. H., and Kalunian, K. C. (1990), Obstet. Gynecol. 75, 630–634.
McNeil, H. P., Simpson, R. J., Chesterman, C. N., and Krilis, S. A. (1991), Proc. Natl. Acad. Sei. USA 87, 4120–4124.
Galli, M., Comfurius, P., Maassen, C, et al. (1990), Lancet 355, 1544–1547.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Parke, A. (1992). The Role of IVIG in the Management of Patients with Antiphospholipid Antibodies and Recurrent Pregnancy Losses. In: Ballow, M. (eds) IVIG Therapy Today. Allergy and Immunology, vol 2. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0417-6_9
Download citation
DOI: https://doi.org/10.1007/978-1-4612-0417-6_9
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-4612-6753-9
Online ISBN: 978-1-4612-0417-6
eBook Packages: Springer Book Archive