Abstract
The polymerase chain reaction (PCR) is an enzymatic process that allows the generation of millions of identical DNA molecules in vitro in a few hours, starting with as little as one copy of DNA (Mullis et al., 1986; Mullis and Faloona, 1987; Saiki et al., 1988). In contrast to conventional cloning, this in vitro amplification process is quick, efficient, and can easily be automated. In addition to its enormous potential for clinical diagnosis PCR has found numerous applications in all fields of biology and medicine (Innis et al., 1990; Erlich, 1989; Erlich etal., 1991).
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Rosenthal, A., Platzer, M., Charnock-Jones, D.S. (1994). Capture PCR: An Efficient Method for Walking Along Chromosomal DNA and cDNA. In: Mullis, K.B., Ferré, F., Gibbs, R.A. (eds) The Polymerase Chain Reaction. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4612-0257-8_19
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DOI: https://doi.org/10.1007/978-1-4612-0257-8_19
Publisher Name: Birkhäuser, Boston, MA
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