Thyrotropin-Releasing Hormone (TRH)
Over the past twenty years, alcoholism and alcohol abuse have been identified as behavioral disorders that arise from an interaction between genetic (biological) and experiential/environmental factors.1 As more is learned about alcoholism, it is clear that an indeterminate number of distinct and separate subgroups of the illness exist.1,2 Advances in the understanding of the transmission of alcoholism and its heterogeneity have not as yet been matched by an understanding of the neurobiological basis for any form of alcoholism. Approaches to address this latter problem have included attempts to develop animal models of alcoholism, studies of the molecular and cellular actions of alcohol, studies of the neurobiological basis of drug-seeking behavior in animals, and studies of the biology of alcoholics and those at risk of developing alcoholism. The latter two strategies are the focus of this chapter.
KeywordsPlacebo Depression Dopamine Cortisol Testosterone
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