Abstract
Colorectal cancer ranks as one of the top three neoplasms in industrialized countries, both in numbers of new cases and numbers of deaths (1). In the United States, there are approximately 150,000 new colorectal cancer cases and 60,000 deaths each year(2).Rates of colorectal cancer are somewhat higher in men than women (1,3), but the numbers of new cases and deaths are roughly equal for both sexes, due to the larger proportion of older women in our population. While colorectal cancer incidence rates in the United States tended to increase over the past several decades, mortality rates remained relatively stable and, in more recent years, both incidence and mortality have shown signs of diminishing(2,4).
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References
Boyle P, Zaridze DG, Smans M: Descriptive epidemiology of colorectal cancer. Int J Cancer 36:9–18, 1985
Chow W-H, Devesa SS, Blot WJ: Colon cancer incidence: recent trends in the United States. Cancer Causes and Control 2:419–425, 1991
Miller BA, Ries LAG, Hankey BF: Cancer Statistics Review: 1973–1989: National Cancer Institute, 1992
Greenwald P: Colon cancer overview. Cancer (Supplement) 70:1206–1215, 1992
Greenberg ER, Baron JA: Prospects for preventing colorectal cancer death. JNCI 85:1182–1184, 1993
Moertel CG: Chemotherapy for colorectal cancer. New Engl J Med 330:1136–42, 1994
Mandel JS, Bond JH, Church TR: Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study. New Engl J Med 328:1365–1371, 1993
Selby JV, Friedman GD, Quesenberry CPJ: A case-control study of screening sigmoidoscopy andmortality from colorectal cancer. NEJM 326:653–657, 1992
Newcomb PA, Norfleet RG, Storer BE, et al: Screening sigmoidoscopy and colorectal cancer mortality. Journal of the National Cancer Institute 84:1572–1575, 1992
Winawer SJ, Zauber AG, Ho MN, et al: Prevention of colorectal cancer by colonoscopic polypectomy. New Engl J Med 329:1977–81, 1993
Boyle P, Zaridze D, Smans M: Descriptive pidemiology of colorectal cancer. Int J Cancer 36:9–18, 1985
Whittemore AS: Colorectal cancer incidence among Chinese in North America and the Peoples Republic of China: variation with sex, age and anatomical site. Int. J Epidemiol 18:563–568, 1989
Shimizu H, Mack TM, Ross RK, et al: Cancer of the gastrointestinal tract among Japanese and White immigrants in Los Angeles county. JNCI 78:223–228, 1987
Willett W: The search for the causes of breast and colon cancer. Nature 338:389–394, 1989
Steinmetz KA, Potter JD: Vegetables, fruit, and cancer. I. Epidemiology. Cancer Causes and Control 2:325–57, 1991
Steinmetz K, Potter J: Vegetables, fruit, and cancer. II Mechanisms. Cancer Causes and Control 2:427–442, 1991
Hennekens CH, Buring JE: Contributions of observational evidence and clinical trials in cancer prevention. Cancer 74:2625–2629, 1994
Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61:759–767, 1990
Peipins LA, Sandler RS: Epidemiology of colorectal adenomas. Epidemiologic Reviews 16:273–297, 1995
Bond JH: Polyp guideline: diagnosis, treatment, and surveillance for patients with nonfamilial colorectal polyps. Ann Intern Med 119:836–843, 1993
McKeown-Eyssen G, Holloway C, Jazmaji V, et al: A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps. Cancer Res 48:4701–4705, 1988
McKeown-Eyssen GE, Bright-See E, Bruce WR, et al: A randomized trial of a low fat high fibre diet in the recurrence of colorectal polyps. Journal of Clinical Epideimology 47:525–536, 1994
Greenberg ER, Baron JA, Tosteson TD, et al: A clinical trial of antioxidant vitamins to prevent colorectal adenoma. New Engl J Med 331:141–147, 1994
Hixson L, Fennerty M, Sampliner R, et al:Prospective study of the frequency and size distribution of polyps missed by colonoscopy. J Natl Cancer Inst 82:1769–1772, 1990
Schatzkin A, Freedman LS, Dawsey SM, et al:Interpreting precursor studies: what polyp trials tell us about large-bowel cancer. Journal of the National Cancer Institute 86:1053–1057, 1994
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Greenberg, E.R. (1995). Nutritional Prevention Trials for Colorectal Neoplasia. In: Prasad, K.N., Santamaria, L., Williams, R.M. (eds) Nutrients in Cancer Prevention and Treatment. Experimental Biology and Medicine, vol 27. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0237-0_16
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DOI: https://doi.org/10.1007/978-1-4612-0237-0_16
Publisher Name: Humana Press, Totowa, NJ
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