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Angiogenesis in Mammary Tumors: Quantitation and Relation to Prognosis

  • Stephen B. Fox
Part of the Cardiovascular Molecular Morphogenesis book series (CARDMM)

Abstract

Angiogenesis is the generation of new vessels from the existing vasculature and is essential for tumor growth and metastasis. This requisite increase in tumor vascularity has been recognized for many centuries. Indeed the tumor vasculature was described posthumously by John Hunter in 1794 who noted, “In a disease in which there is an increase in the part, as in tumors, the increase in the vessels is conspicuous.” However, it is only since Folkman’s (1971) hypothesis on antiangiogenesis that a quantitative method for measuring angiogenesis has been pursued.

Keywords

Breast Cancer Vascular Endothelial Growth Factor Breast Carcinoma Mammary Tumor Tumor Angiogenesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 2001

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  • Stephen B. Fox

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