Lung Volume Reduction Surgery for Severe Emphysema
Lung volume reduction surgery (LVRS) was reincarnated in the early 1990s as a promising therapy to palliate symptoms and improve quality of life in patients disabled by severe emphysema. Controversy regarding the reliability and risks of the surgery as well as long-term durability stifled the initial proliferation of LVRS and led to the historic National Emphysema Treatment Trial (NETT). There are now strong data from large case-controlled series, from several small randomized trials, and from the large randomized multi-institutional NETT that confirm improvement in pulmonary function, exercise capacity, and quality of life in select patients with severe emphysema.
KeywordsEmphysema Lung reduction LVRS
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