Atrial Fibrillation

  • Vincent E. Friedewald


Calculate CHA2DS2-VASc SCORE for thromboembolic risk [26]


Fatigue Influenza Heparin Cardiomyopathy Statin 


  1. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities Google Scholar
  2. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation Google Scholar
  3. Antiplatelet drugs: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of chest physicians evidence-based clinical practice guidelines Google Scholar
  4. 2012 HRS/EHRA/ECAS Expert Consensus Statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design Google Scholar
  5. The Indian consensus guidance on stroke prevention in atrial fibrillation: an emphasis on practical use of nonvitamin K oral anticoagulants Google Scholar

Professional Information

Review: Acute Management

Review: Anticoagulation

Review: Cardiac Fibrosis

Review: Effects Beyond Atrium

Review: Atrial Fibrillation/Heart Failure

Review: Aniarrhythmic Drug Therapy

  1. Circ Arrhythmia Electrophysiol. 2016;9:e002479. doi: 10.1161/CIRCEP.115.002479.

Review: LAA Occlusion

Review: LAA Occlusion

Review: Pathophysiology

Review: Progression from Paroxysmal to Persistent AF

Review: Stroke Prevention

Review: Stroke Prevention

Ablation: Antiarrhythmic Drugs Following

Ablation: Effect on GI Motility

  1. Circulation: Arrhythmia and Electrophysiology. 2015;8:531–6.

Ablation: Gastroparesis as Complication

Ablation: Response/Genetic Variants

  1. Circulation: Arrhythmia and Electrophysiology. 2015;8:296–302.

ACEIS/ARBS for Prevention

Acute Myocardial Infarction/Death

  1. Circulation. 2011;123:2094–100.

Acute Pericarditis

Acute Pulmonary Embolism

  1. J Am Heart Assoc. 2014;3:e000483.

Acute Pulmonary Embolism Risk: CHA2DS2-VASC Score

AF/HF: Quality of Life/Functional Capacity

AF-Related Embolism: Epidemiology

Aerobic Training: Prevention

African Americans: European Ancestry

Air Pollution

Alcohol Consumption: Risk Factor

Alcohol Consumption: Meta-analysis

Alcohol Consumption: Prognosis

Alcohol Consumption: Women



Anemia/Decreased Renal Function


Aortic Stenosis

Aortic Stenosis


Atrial Fibrillation Risk

Atrial Fibrosis

Atrial Fibrosis

Atrial Fibrosis

Atrial Septal Defect


  1. N Engl J Med. 2011;365:981–92.

Atrial Fibrilation/Atrial Flutter

Atrial Fibrillation/Atrial Flutter: ECG Misdiagnosis

Atrial Remodeling

Atrial Remodeling

  1. Circ Arrhythm Electrophysiol. 2008;1:62–73.

Autonomic Ganglia In AF

Bile Acid Composition Effects



Botulinum Toxin Injection for Recurrence Prevention



Cardiac Surgery

Cardiorespiratory Fitness

Cardioversion: Hemodynamic/Exercise Changes

Cardioversion: Post-procedure Thromboembolism

Cognitive Impairment in PTS with HF

Coronary Artery Calcium

  1. Am J Cardiol. 2014;114:1707–12.

Catheter Ablation

Catheter Ablation

Catheter Ablation: Persistent AF

  1. N Engl J Med. 2015;372:1812–22.

Catheter Ablation: Post-procedure Cognitive Dysfunction

Catheter Ablation Versus Drug Therapy

Cholinergic Atrial Fibrillation

CNS Protection (Editorial)

Coffee Consumption

  1. Eur J Prev Cardiol. 2015. pii: 2047487315624524.

Cognitive Impairment

Cognitive Impairment

CRT: Review of 20 Year Experience


  1. N Engl J Med. 2013;369:1206–14.


Dengue Fever

  1. Braz J Infect Dis. 2003;7:418–22.

Diabetes Mellitus: Stroke Risk

Diabetes Mellitus: Subclinical AF/CNS Effects


Digoxin: Risk of Death/Hospitalization

  1. Circulation: Arrhythmia and Electrophysiology. 2015;8:49–58.



  1. N Engl J Med. 2011;365:2268–76.

Dronedarone: Safety

Early Onset Atrial Fibrillation: KCNA5 Variants

Epicardial Adipose Tissue


Ethnicity/Stroke Risk

Familial Atrial Fibrillation

Fish Oil

Galactin-3 Level: Persistent a FIB


  1. Circulation Research. 2014;114:1469–82.

Genetics: SCN10A

  1. Circulation: Cardiovascular Genetics. 2015;8:64–73.

Head Trauma

  1. Emerg Med J. 2003;20:106–8.

Heart Failure

Heart Failure: Catheter Ablation

  1. N Engl J Med. 2004;351:2373–83.

Heart Failure: AF (New Onset) as Predictor of Progression

Heart Failure/Stroke: Symptoms/LV Dysfunction

Heart Transplant

  1. J Cardiovasc Electrophysiol. 2006;17:827–31.


Hypertension: Risk Model for AF



Hypertrophic Cardiomyopathy


  1. Ann Emerg Med. 1990;19:565–7.


Hypothermia: Post-cardiopulmonary Bypass

  1. Crit Care Med. 2000;28:309–11.

Imaging (Noninvasive)

Incidence/Risk Factor for AF in Older Adults (CV Health Study)

Inflammation: Risk Factor

LAA Occlusion: DECR P Wave Dispersion

  1. J Am Heart Assoc. 2015;4:e001581.

LAA Occlusion: Metaanalysis

LAA Occlusion: Prevail Trial (Watchman)

LAA Occlusion: Percutaneous – Lariat

LAA Occlusion

LAA Occlusion

Left Atrial Stiffness

  1. Circ Arrhythmia Electrophysiol. 2016;9:e003163. doi: 10.1161/CIRCEP.115.003163

Left Atrial Structure/Function

Lone Atrial Fibrillation: Histology

Lung Function Reduction: Increased Risk of AF


Mass Screening

Metabolic Syndrome

Mitral Annulus Calcification

  1. Europace. 2014. (Epub ahead of print).

Mitral Annulus Calcification

  1. Atherosclerosis. 2004;173:291–4.

Mitral Regurgitation

Mitral Stenosis/La Thrombus

  1. Am J Cardiol. 2000;86:529–34.

Molecular Pathophysiology

  1. J Clin Invest. 2011;121:2955–68.

Mortality Risk

Muscular Dystrophy




Obesity: Risk for Atrial Fibrillation

Obstructive Sleep Apnea

Obstructive Sleep Apnea/Stroke

Obstructive Sleep Apnea Treatment: AF Recurrence

Oral Antithrombotics (AHA Science Advisory)

Outcomes: Long-Term (Framingham)

P Wave Duration: Risk

Pathophysiology/Prognosis: Imaging

  1. Circulation: Cardiovascular Imaging. 2015;8:e003020.

Pericarditis: Acute

Pericarditis: Constrictive

  1. Ann Noninvasive Electrocardiol. 2009;14:258–61.

Perioperative Atrial Fibrillation

Peripheral Artery Disease

  1. J Am Heart Assoc. 2014;3:e001270.


  1. Rev Port Cardiol. 2014;33:245.e1–4.


  1. Clin Infect Dis. 2007;45:158–65.

Predisposing Factors

Preexcitation Syndromes


QTC Duration/AF Risk

Rate Control

  1. N Engl J Med. 2010;362:1363–73.

Rate/Rhythm Control: Review

  1. Ann Intern Med. 2014;160:760–73.

Renal Dysfunction: Anticoagulants

Rhythm Control: La Dysfunction

Risk Factors: Framingham Heart Study

Risk: Long-Term

Risk: Resting HR/Physical Activity

Risk for Stroke/Bleeding Associated with Antithrombotic Therapy


  1. N Engl J Med. 2011;365:883–91.

Second Hand Smoke Exposure

Sick Sinus Syndrome

Silent Cerebral Ischemia

Silent Stroke

  1. Ann Intern Med. 2014;161:650–8.

Spinal Cord Injury

Statins: Post-OP AF Prevention

  1. J Thorac Cardiovasc Surg. 2010;139:803–4.


  1. N Engl J Med. 2014;370:2467–77.

Stroke: Prevention in Patients with CKD

  1. Circulation. 2016; 133:1512–15.

Stroke: Subclinical AF

Systemic Arterial Hypertension

  1. Am J Cardiol. 2003;91:9G–14G.

Systemic Emboli

Thoracic Surgery

Thromboembolism Risk: CHA2DS2-VASc Score

Vigorous Exercise

Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  • Vincent E. Friedewald
    • 1
  1. 1.Division of CardiologyUT Health Science Center at Houston Division of CardiologyHoustonUSA

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