Evolution of the Cryo-lesion

  • Christopher M. Scott
  • Gloria F. Graham
  • Ronald R. Lubritz


Expected results after freezing are erythema, urtication, and edema which may last for several days. If freezing is superficial, vesicles or bullae developed. Bullae may become hemorrhagic. When treating malignances, a more gelatinous appearance may result. The stroma is more resistant to freezing than the cellular elements. Healing for most lesions takes place within 2 weeks for benign or premalignant lesions to 4–6 weeks for malignant lesions. Systemic steroids may be used to prevent swelling around the periorbital area.

 Hemorrhaging should be controlled by aluminum chloride, Monsel’s solution or electrodessication. Anti-inflammatory and anti-coagulants have rarely caused prolonged bleeding. Secondary infection is rare but responds to topical or systemic antibiotics.


Cryosurgery Hemorrhagic bullae Edema Urtication Erythema 


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Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  • Christopher M. Scott
    • 1
  • Gloria F. Graham
    • 2
  • Ronald R. Lubritz
    • 3
  1. 1.Department of DermatologyUniversity of VirginiaCharlottesvilleUSA
  2. 2.Department of DermatologyWake Forest University School of MedicineWinston SalemUSA
  3. 3.Department of DermatologyTulane University School of Medicine, Hattiesburg ClinicHattiesburgUSA

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