Prurigo nodularis (PN) is a chronic skin disorder of unknown aetiology characterized by intensely pruritic and excoriated nodules, mainly located symmetrically on the bilateral extensor extremities, the number of which may vary from a few to hundreds. The treatment of PN is often frustrating. Topical antipruritics, localized phototherapy and photochemotherapy, systemic corticosteroids and cyclosporine have been employed. PN has been treated successfully with blistering cryotherapy. When scarring begins, the patient experiences a remarkable decrease in itching.
KeywordsPrurigo nodularis Cryotherapy
- 5.Graham GF. Cryosurgery in treatment of acne and specific cutaneous neoplasia. In: Zacarian SA, editor. Cryosurgical advances in dermatology and tumors of the head and neck. Springfield: Charles C Thomas; 1977. p. 74–97.Google Scholar
- 7.Siepmann D, Luger TA, Ständer S. Antipruritic effect of cyclosporine microemulsion in prurigo nodularis: results of a case series. J Dtsch Dermatol. 2008;6:941–6.Google Scholar
- 10.Mattos O. Prurigo nodular de Hyde tratado com talidomida. Bol Div Nac Lepra. 1973;32:71–7.Google Scholar
- 11.Winkelmann RK, Connolly SM, Doyle JA, Gonçalves AP. Thalidomide treatment of prurigo nodularis. Acta Derm Venereol (Stockh). 1984;64:412–7.Google Scholar