Abstract
Angiography identifies minimal luminal diameter but does not calculate the minimal luminal area. The operator should keep in mind the limitations of angiography. A significant lesion may be missed due to its eccentric nature, location in a highly tortuous artery, ostial position, or length. In addition, moderate (50–70 %) lesions may be hemodynamically significant (see Fig. 4.1). Fractional flow reserve [FFR] provides objective evidence for functional significance. FFR-guided decision making provides better clinical outcomes when compared to angiography, and therefore every operator must be familiar with this technique.1
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Tonino PA, De Bruyne B, Pijls NH. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360(3):213–24
De Bruyne B, Pijls NH, Kalesan B. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367(11):991–1001.
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© 2014 Springer-Verlag London
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Senguttuvan, N.B., Rajamanickam, A., Kini, A. (2014). Physiological Assessment During Interventional Procedures. In: Kini, A., Sharma, S., Narula, J. (eds) Practical Manual of Interventional Cardiology. Springer, London. https://doi.org/10.1007/978-1-4471-6581-1_4
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DOI: https://doi.org/10.1007/978-1-4471-6581-1_4
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