Aneurysmal Bone Cyst
Aneurysmal bone cyst is an intramedullary eccentric metaphyseal and rapid expansible benign lytic lesion with multiloculated blood-filled cystic cavities, lined by membranes of different thickness and composed of spindle cells, osteoid trabeculae, and osteoclastic-type giant cells. Primary ABC: When ABC arises “de novo” in bone − 70 % of cases. In these cases, a definite preexisting lesion cannot be demonstrated. Secondary ABC: Areas similar to primary ABC are found in various benign and malignant conditions. Male/female ratio is equal. The second followed by the first decade of life accounts for 80 % of cases. Roentgenographically, it is an area of lucency situated eccentrically in the medullary cavity in the metaphysis of a long bone. MRI confirms the entirely cystic nature, the internal septations, and its fluid-fluid levels. Treatment includes excision or curettage and bone grafting.
KeywordsAneurysmal bone cyst Pseudotumor Genetics Secondary aneurysmal bone cyst
- Sukov WRD, Franco MF, Erickson-Johnson M, Chou MM, Unni KK, Wenger DE, Wang X, Oliveira AM. Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of “myositis ossificans-like lesions” are the early phases in the formation of soft-tissue aneurysmal cyst. Skeletal Radiol. 2008;37(4):321–7.CrossRefPubMedGoogle Scholar